SCHEMBL3390987

SCHEMBL3390987

C[C@@]1(N)CCCNC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3390990 1.00
SCHEMBL22010942 1.00
Hydrochloric Acid SCHEMBL2086295 0.97 SOS1 (0.31)
Hydrochloric Acid SCHEMBL2086297 0.97 SOS1 (0.31)
SCHEMBL19825217 0.92
SCHEMBL28693668 0.92
SCHEMBL13806584 0.90 ALDH1A1 (0.36)
SCHEMBL4515477 0.83
SCHEMBL14222410 0.83
SCHEMBL14222411 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304599-A1 MACROCYCLIC COMPOUNDS AND METHODS OF USE AMGEN INC. (US) 2025-10-02 US disclosed
WO-2021032170-A1 TETRACYCLIC COMPOUND USED AS CDC7 INHIBITOR 南京明德新药研发有限公司 2021-02-25 WO disclosed
US-10865216-B2 Tricyclic Gyrase inhibitors MERCK SHARP & DOHME CORP. (US) 2020-12-15 US disclosed
US-10378700-B2 LED tube lamp JIAXING SUPER LIGHTING ELECTRIC APPLIANCE CO., LTD. (CN) 2019-08-13 US disclosed
CN-102134230-B Dipeptidyl peptidase inhibitors 武田药品工业株式会社 2019-06-28 CN disclosed
CN-103848835-B Dipeptidyl peptidase-iv inhibitor, its purposes and its preparation method of intermediate and intermediate 上海阳帆医药科技有限公司 2018-07-06 CN disclosed
CN-103848835-A Dipeptidyl peptidase-IV inhibitor, application thereof, intermediate body thereof and preparation method of intermediate body thereof SHANGHAI SUN SAIL PHARMACEUTICAL SCIENCE & TECHNOLOGY CO LTD 2014-06-11 CN disclosed
EP-1911754-B1 Dipeptidyl peptidase inhibitors TAKEDA PHARMACEUTICAL (JP) 2013-10-09 EP disclosed
US-7790736-B2 Dipeptidyl peptidase inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-09-07 US disclosed
US-7723344-B2 Dipeptidyl peptidase inhibitors TAKEDA SAN DIEGO, INC. (US) 2010-05-25 US disclosed
US-20050075330-A1 Dipeptidyl peptidase inhibitors SYRRX, INC. 2005-04-07 US disclosed
WO-2005030751-A2 DIPEPTIDYL PEPTIDASE INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-04-07 WO disclosed
US-20050070535-A1 Dipeptidyl peptidase inhibitors SYRRX, INC. 2005-03-31 US disclosed
US-20050070531-A1 Dipeptidyl peptidase inhibitors SYRRX, INC. 2005-03-31 US disclosed
US-20050070706-A1 Dipeptidyl peptidase inhibitors SYRRX, INC. 2005-03-31 US disclosed
US-20050070530-A1 Dipeptidyl peptidase inhibitors SYRRX, INC. 2005-03-31 US disclosed
US-20050065148-A1 Dipeptidyl peptidase inhibitors SYRRX, INC. 2005-03-24 US disclosed
WO-2005016911-A1 4-PYRIMIDONE DERIVATIVES AND THEIR USE AS PEPTIDYL PEPTIDASE INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-02-24 WO disclosed
WO-2005016911-A1 4-PYRIMIDONE DERIVATIVES AND THEIR USE AS PEPTIDYL PEPTIDASE INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-02-24 WO disclosed
EP-1506967-A1 Dipeptidyl peptidase inhibitors Syrrx, Inc. (US) 2005-02-16 EP disclosed