SCHEMBL3391309

SCHEMBL3391309

c1ccc(-c2nccnn2)nc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 6/20 0.64
KDM4E B2RXH2 9/20 0.58
TDP1 Q9NUW8 3/20 0.58
LMNA P02545 3/20 0.54
CCR1 P32246 2/20 0.54
CCR5 P51681 2/20 0.54
CCR8 P51685 2/20 0.54
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54
METAP1 P53582 1/20 0.54
BLM P54132 1/20 0.54
HIF1A Q16665 1/20 0.54
DOHH Q9BU89 1/20 0.54
P4HTM Q9NXG6 1/20 0.54
NPC1 O15118 7/20 0.52
RAB9A P51151 6/20 0.52
L3MBTL1 Q9Y468 5/20 0.52
SMN1; SMN2 Q16637 5/20 0.52
ALOX15 P16050 4/20 0.52
PKM P14618 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31268013 0.81 KDM4E (0.75) TP53KDM4ETDP1LMNACCR1
SCHEMBL580823 0.81 KDM4E (0.75) TP53KDM4ETDP1LMNACCR1
SCHEMBL11039070 0.80 KDM4E (0.43) TP53KDM4ETDP1LMNACCR1
SCHEMBL13977588 0.80 TP53 (0.74) TP53KDM4ETDP1LMNACCR1
SCHEMBL29636540 0.80 KDM4E (0.43) TP53KDM4ETDP1LMNACCR1
SCHEMBL25493617 0.80 TP53 (0.38) TP53KDM4ETDP1LMNACCR1
Hydrochloric Acid SCHEMBL28577751 0.79 KDM4E (0.71) TP53KDM4ETDP1LMNACCR1
SCHEMBL30694104 0.79 TP53 (1.00) TP53KDM4ETDP1LMNACCR1
SCHEMBL2852298 0.79 TP53 (1.00) TP53KDM4ETDP1LMNACCR1
SCHEMBL29767699 0.79 TP53 (1.00) TP53KDM4ETDP1LMNACCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2010514-B1 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES BASF SE (DE) 2010-12-29 EP claimed
US-20090111692-A1 3-(Pyridin-2-Yl)-[1,2,4]-Triazines as Fungicides BASF AKTIENGESELLSCHAFT (DE) 2009-04-30 US claimed
CN-114471474-B Resin material capable of selectively adsorbing Am (III) in high acid environment and preparation method thereof 兰州大学 2023-09-08 CN disclosed
CN-114471474-A Resin material capable of selectively adsorbing am (III) in high-acid environment and preparation method thereof 兰州大学 2022-05-13 CN disclosed
CN-113286777-A Compounds, compositions and methods for modulating iron death and treating excitotoxic disorders 纽约市哥伦比亚大学理事会 2021-08-20 CN disclosed
EP-3048155-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC COMPONENTS cynora GmbH (DE) 2016-07-27 EP disclosed
EP-3048156-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC COMPONENTS cynora GmbH (DE) 2016-07-27 EP disclosed
CN-103547578-A 2,9-dipyridyl-1,10-phenanthroline derivatives useful as actinide ligands, method for synthesizing same, and uses thereof COMMISSARIAT ENERGIE ATOMIQUE 2014-01-29 CN disclosed
EP-2010514-B1 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES BASF SE (DE) 2010-12-29 EP disclosed
EP-2010514-B1 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES BASF SE (DE) 2010-12-29 EP disclosed
EP-2010514-B1 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES BASF SE (DE) 2010-12-29 EP disclosed
WO-2003079737-A2 RHENIUM COMPOUNDS AND THEIR USE IN ELECTROLUMINESCENT VORRICHTUNGEN ISIS INNOVATION LIMITED (GB) 2003-09-25 WO disclosed
US-5912180-A MIXING LIQUID SAMPLES WITH BORATE CAUSING LEAD TO PRECIPITATE, FILTERING PRECIPITATE FROM LIQUID, TESTING BY CONTACTING PRECIPITATE WITH REAGENT CAUSING COLORIMETRIC REACTION; FOR POLLUTION CONTROL HYBRIVET SYSTEMS, INC. (US) 1999-06-15 US disclosed
US-5567619-A PRECIPITATION, FILTRATION, COLORIMETRIC ANALYSIS HYBRIVET SYSTEMS, INC. (US) 1996-10-22 US disclosed
US-5550061-A SWAB FOR TESTING FOR METAL ON SURFACE HAVING HOLLOW STEM WITH PASSAGEWAY TO ABSORBENT BALL OF MATERIAL AT ONE END CONTAINING CRUSHABLE CARTRIDGE OF INDICATOR REAGENT AND SECOND CRUSHABLE CARTRIDGE OF ACTIVATOR HYBRIVET SYSTEMS, INC. (US) 1996-08-27 US disclosed
US-5496736-A COLORIMETRIC HYBRIVET SYSTEMS, INC. (US) 1996-03-05 US disclosed
US-5416028-A Process for testing for substances in liquids HYBRIVET SYSTEMS, INC. (US) 1995-05-16 US disclosed
US-5364792-A Metal surface testing with swabs containing absorbent balls and reagents HYBRIVET SYSTEMS, INC. (US) 1994-11-15 US disclosed
US-5330917-A Rubbing absorbent ball impregnated with reagent over surface; colorimetric analysis HYBRIVET SYSTEMS, INC. (US) 1994-07-19 US disclosed
US-5278075-A Testing for metal /or organophosphate/ on solid surface by providing swab stick carrying absorbent ball impregnated with reagent, contacting ball with surface, detecting metal by inspecting ball for reaction between metal and reagent; kit HYBRIVET SYSTEMS, INC. (US) 1994-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090111692-A1 3-(Pyridin-2-Yl)-[1,2,4]-Triazines as Fungicides CBR3, CBR1, TH TP53 3521/4885KDM4E 1789/4885TDP1 2894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.