SCHEMBL339147

SCHEMBL339147

O=P(O)(O)Oc1cccc(Cc2ccccc2)c1Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 2/20 0.47
INPP5A Q14642 2/20 0.47
INPP5B P32019 1/20 0.47
SRC P12931 3/20 0.46
HPGD P15428 2/20 0.46
KDM4E B2RXH2 1/20 0.46
USP2 O75604 1/20 0.46
ALDH1A1 P00352 1/20 0.46
PDE3A Q14432 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ALPG P10696 1/20 0.40
PTK2B Q14289 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PPM1D O15297 1/20 0.39
TSHR P16473 1/20 0.39
HSP90AA1 P07900 1/20 0.38
HRH1 P35367 3/20 0.38
AKT1 P31749 1/20 0.38
DRD2 P14416 1/20 0.38
DRD1 P21728 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4445999 0.87 HPGD (0.41) HPGDSMN1; SMN2TSHRHSP90AA1HRH1
SCHEMBL1099381 0.87 SRC (0.51) INPPL1INPP5AINPP5BSRCHPGD
Phosphoric Acid SCHEMBL28329170 0.81 DRD1 (0.42) HPGDKDM4EALPGPTK2BSMN1; SMN2
Ether SCHEMBL8746887 0.80 SRC (0.37) INPPL1INPP5AINPP5BSRCHPGD
SCHEMBL29965134 0.80 INPPL1 (0.46) INPPL1INPP5AINPP5BSRCHPGD
SCHEMBL7033288 0.79 HPGD (0.49) HPGDSMN1; SMN2TSHRHRH1DRD2
Sulfuric Acid SCHEMBL30659040 0.78 TP53 (0.42) HPGDSMN1; SMN2TSHRHSP90AA1HRH1
SCHEMBL18529842 0.77 KDM4E (0.40) INPPL1INPP5AINPP5BSRCHPGD
SCHEMBL15559464 0.77 SRC (0.51) SRCHPGDALPGPTK2BSMN1; SMN2
Ethylene SCHEMBL28237007 0.76 HPGD (0.46) HPGDSMN1; SMN2TSHRHRH1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115725123-A Method for incorporating graphene into rubber complexes using a liquid plasticizer route-LPR method 福特全球技术公司 2023-03-03 CN claimed
US-20120015908-A1 SYNTHESIS AND ANTICANCER ACTIVITY OF ARYL AND HETEROARYL-QUINOLIN DERIVATIVES Efficient Pharma Management Corporate (TW) 2012-01-19 US claimed
CN-115485316-A Polyol block copolymers 艾柯尼克技术有限公司 2022-12-16 CN disclosed
EP-3112348-A1 SYNTHESIS AND ANTICANCER ACTIVITY OF ARYL AND HETEROARYL-QUINOLIN DERIVATIVES Tairx, Inc. (TW) 2017-01-04 EP disclosed
US-20090027586-A1 Thermoplastic Resin Composition, and Liquid Crystal Display Component Thereof or Information Recording Media Component Thereof POLYPLASTICS CO., LTD. (JP) 2009-01-29 US disclosed
EP-1992666-A1 THERMOPLASTIC RESIN COMPOSITION AND LIQUID CRYSTAL DISPLAY PART OR INFORMATION RECORDING MEDIUM PART USING THE COMPOSITION Polyplastics Co., Ltd. (JP) 2008-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015908-A1 SYNTHESIS AND ANTICANCER ACTIVITY OF ARYL AND HETEROARYL-QUINOLIN DERIVATIVES SLC22A8, ABCC8, CYP2C8 INPPL1 2278/4885INPP5A 4150/4885INPP5B 3972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.