1,5-Pentanediol

1,5-Pentanediol

SCHEMBL3391585

CC(=O)O.O=CO.OCCCCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of 1,5-Pentanediol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.48
FFAR1 O14842 1/20 0.48
FFAR4 Q5NUL3 1/20 0.48
LMNA P02545 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CAMK2A Q9UQM7 1/20 0.39
FFAR3 O14843 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
FNTA P49354 1/20 0.37
FNTB P49356 1/20 0.37
CYP4F2 P78329 2/20 0.33
CYP4A11 Q02928 2/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,6-Hexanediol SCHEMBL3387365 1.00 GPR84 (0.48) GPR84FFAR1FFAR4LMNAALDH1A1
1,4-Butanediol SCHEMBL2161930 0.97 GPR84 (0.43) GPR84FFAR1FFAR4LMNAALDH1A1
1,3-Propanediol SCHEMBL2160749 0.92 FFAR3 (0.41) GPR84FFAR1FFAR4LMNAALDH1A1
Acetic Acid SCHEMBL28557074 0.88 GPR84 (0.58) GPR84FFAR1FFAR4LMNAALDH1A1
Acetic Acid SCHEMBL11291740 0.88 GPR84 (0.58) GPR84FFAR1FFAR4LMNAALDH1A1
1,5-Pentanediol SCHEMBL5373304 0.88 GPR84 (0.58) GPR84FFAR1FFAR4LMNAALDH1A1
1,6-Hexanediol SCHEMBL28434993 0.88 GPR84 (0.58) GPR84FFAR1FFAR4LMNAALDH1A1
1,5-Pentanediol SCHEMBL6419062 0.88 GPR84 (0.58) GPR84FFAR1FFAR4LMNAALDH1A1
Acetic Acid SCHEMBL11292613 0.88 GPR84 (0.58) GPR84FFAR1FFAR4LMNAALDH1A1
Acetic Acid SCHEMBL27942742 0.88 GPR84 (0.58) GPR84FFAR1FFAR4LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1729365-B1 NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING THE SAME UBE INDUSTRIES (JP) 2010-12-22 EP disclosed
US-20080241704-A1 Nonaqueous Electrolyte Solution and Lithium Secondary Battery Using Same UBE INDUSTRIES, LTD (JP) 2008-10-02 US disclosed
EP-1729365-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME Ube Industries, Ltd. (JP) 2006-12-06 EP disclosed