Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3199290 | 0.83 | HTR6 (0.43) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL3394481 | 0.82 | HTR6 (0.39) | HTR6 | |
| SCHEMBL3204610 | 0.81 | HTR6 (0.43) | HTR6 | |
| SCHEMBL3194665 | 0.81 | HTR6 (0.42) | HTR6HTR1A | |
| SCHEMBL3217047 | 0.81 | HTR6 (0.42) | HTR6HTR1A | |
| SCHEMBL3204978 | 0.81 | HTR6 (0.42) | HTR6HTR1A | |
| SCHEMBL3203594 | 0.80 | HTR6 (0.42) | HTR6 | |
| SCHEMBL3203927 | 0.80 | HTR6 (0.61) | HTR6HTR1ADRD2 | |
| SCHEMBL3204063 | 0.80 | HTR6 (0.61) | HTR6HTR1ADRD2 | |
| SCHEMBL3215266 | 0.80 | HTR6 (0.61) | HTR6HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011546-A2 | ACYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-28 | — | — | WO | claimed |