Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.70 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5305854 | 0.92 | L3MBTL1 (0.70) | L3MBTL1OPRK1MAPTF2KCNH2 | |
| SCHEMBL11653014 | 0.89 | L3MBTL1 (0.86) | L3MBTL1MEN1GAAMAPTKMT2A | |
| SCHEMBL24152726 | 0.89 | L3MBTL1 (0.56) | L3MBTL1OPRK1RAB9ANPC1MTOR | |
| SCHEMBL21186859 | 0.85 | L3MBTL1 (0.95) | L3MBTL1MEN1GAAMAPTKMT2A | |
| SCHEMBL88597 | 0.85 | L3MBTL1 (0.95) | L3MBTL1MEN1GAAMAPTKMT2A | |
| SCHEMBL24375975 | 0.85 | L3MBTL1 (0.95) | L3MBTL1MEN1GAAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL8746161 | 0.83 | L3MBTL1 (1.00) | L3MBTL1MEN1GAAMAPTKMT2A | |
| SCHEMBL3910280 | 0.82 | L3MBTL1 (0.73) | L3MBTL1MEN1GAAMAPTKMT2A | |
| SCHEMBL819106 | 0.82 | L3MBTL1 (0.80) | L3MBTL1MEN1GAAMAPTKMT2A | |
| SCHEMBL24641654 | 0.82 | L3MBTL1 (0.73) | L3MBTL1GAAMAPTF2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393362-B1 | NOVEL BENZODIAZEPINE DERIVATIVES | IMMUNOGEN INC (US) | 2016-08-24 | — | — | EP | disclosed |
| EP-2948135-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PERVASIVE DEVELOPMENT DISORDERS | Case Western Reserve University (US) | 2015-12-02 | — | — | EP | disclosed |
| WO-2014117089-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PERVASIVE DEVELOPMENT DISORDERS | CASE WESTERN RESERVE UNIVERSITY (US) | 2014-07-31 | — | — | WO | disclosed |
| US-20100135855-A1 | METHOD FOR DEPOSITING SUBSTANCES ON A SUPPORT | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2010-06-03 | — | — | US | disclosed |
| EP-1545613-A4 | DRUG CONJUGATES AND THEIR USE FOR TREATING CANCER, AN AUTOIMMUNE DISEASE OR AN INFECTIOUS DISEASE | SEATTLE GENETICS INC (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007017652-A2 | ARYLAKYLAMINES FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | disclosed |
| EP-1545613-A2 | DRUG CONJUGATES AND THEIR USE FOR TREATING CANCER, AN AUTOIMMUNE DISEASE OR AN INFECTIOUS DISEASE | Seattle Genetics, Inc. (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004010957-A2 | DRUG CONJUGATES AND THEIR USE FOR TREATING CANCER, AN AUTOIMMUNE DISEASE OR AN INFECTIOUS DISEASE | SEATTLE GENETICS, INC. (US) | 2004-02-05 | — | — | WO | disclosed |
| EP-1115579-A1 | MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Ciba SC Holding AG (CH) | 2001-07-18 | — | — | EP | disclosed |
| EP-1107972-A1 | PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN | Ciba SC Holding AG (CH) | 2001-06-20 | — | — | EP | disclosed |
| EP-0831081-B1 | Production of aminophenols | CIBA SC HOLDING AG (CH) | 2000-11-02 | — | — | EP | disclosed |
| WO-2000026037-A1 | HEAT SENSITIVE RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-05-11 | — | — | WO | disclosed |
| WO-2000012513-A1 | NOVEL PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-09 | — | — | WO | disclosed |
| WO-2000012318-A1 | MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-09 | — | — | WO | disclosed |
| US-5908961-A | UNDER AQUEOUS ACIDIC CONDITIONS; CONTINUOUS MONITORING OFPH | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-06-01 | — | — | US | disclosed |
| EP-0831081-A1 | Production of aminophenols | Ciba SC Holding AG (CH) | 1998-03-25 | — | — | EP | disclosed |