SCHEMBL3392102

SCHEMBL3392102

CCCCOC1CCCC2(C1)NC(=O)C(c1c(C)cc(C)cc1C)=C2O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ACACB O00763 7/20 0.34
ACACA Q13085 7/20 0.34
ELANE P08246 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13963601 1.00 ACACB (0.34) ACACBACACAELANENPC1RAB9A
SCHEMBL13255427 1.00 ACACB (0.34) ACACBACACAELANENPC1RAB9A
SCHEMBL14823118 0.94 ACACB (0.32) ACACBACACA
SCHEMBL12214976 0.94 ACACB (0.38) ACACBACACA
SCHEMBL14464277 0.87 ACACB (0.42) ACACBACACA
SCHEMBL14464235 0.86 ACACB (0.37) ACACBACACA
SCHEMBL11990112 0.85 ACACB (0.43) ACACBACACANPC1RAB9A
SCHEMBL13070119 0.85 ELANE (0.34) ELANE
SCHEMBL13963574 0.84
SCHEMBL13963607 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8410289-B2 Spirocyclic 3'-alkoxytetramic acids and-tetronic acids BAYER CROPSCIENCE AG (DE) 2013-04-02 US disclosed
US-8410289-B2 Spirocyclic 3'-alkoxytetramic acids and-tetronic acids BAYER CROPSCIENCE AG (DE) 2013-04-02 US disclosed
EP-1761490-B1 3'-ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACIDS BAYER CROPSCIENCE AG (DE) 2011-09-07 EP disclosed
EP-2246328-A1 3'-Alkoxy spirocyclic tetronic acid derivatives Bayer CropScience AG (DE) 2010-11-03 EP disclosed
EP-2246328-A1 3'-Alkoxy spirocyclic tetronic acid derivatives Bayer CropScience AG (DE) 2010-11-03 EP disclosed
US-20090029858-A1 Spirocyclic 3'-Alkoxytetramic Acids and -Tetronic Acids BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2009-01-29 US disclosed
US-20090029858-A1 Spirocyclic 3'-Alkoxytetramic Acids and -Tetronic Acids BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2009-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090029858-A1 Spirocyclic 3'-Alkoxytetramic Acids and -Tetronic Acids DDT, MTX1, MTX2 ACACB 505/4885ACACA 230/4885ELANE 4664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.