SCHEMBL3392143

SCHEMBL3392143

Nc1c2c(N)c(c3c1CCC3)CC2

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.48
MEN1 O00255 1/20 0.48
MAPK1 P28482 1/20 0.48
KMT2A Q03164 1/20 0.48
BPTF Q12830 1/20 0.48
BCHE P06276 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL337198 1.00 ACHE (0.48) ACHEMEN1MAPK1KMT2ABPTF
SCHEMBL25198544 0.79 ACHE (0.42) ACHEMEN1MAPK1KMT2ABPTF
SCHEMBL25198553 0.79 ACHE (0.42) ACHEMEN1MAPK1KMT2ABPTF
SCHEMBL7581083 0.78 ACHE (0.32) ACHEMEN1MAPK1KMT2ABPTF
SCHEMBL19475249 0.75 ACHE (0.44) ACHEMEN1MAPK1KMT2ABPTF
SCHEMBL21962356 0.75 ACHE (0.44) ACHEMEN1MAPK1KMT2ABPTF
SCHEMBL18007560 0.75 ACHE (0.44) ACHEMEN1MAPK1KMT2ABPTF
SCHEMBL18007707 0.75 ACHE (0.44) ACHEMEN1MAPK1KMT2ABPTF
SCHEMBL18007601 0.75 ACHE (0.44) ACHEMEN1MAPK1KMT2ABPTF
SCHEMBL20681022 0.69 ACHE (0.39) ACHEMEN1MAPK1KMT2ABPTF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100159228-A1 Method for Preparing a Composite Material ISOTHANE LIMITED (GB) 2010-06-24 US disclosed
US-7674193-B2 Golf ball SRI SPORTS LIMITED (JP) 2010-03-09 US disclosed
US-20040029652-A1 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2004-02-12 US disclosed