SCHEMBL3392354

SCHEMBL3392354

Oc1cc(CN(CCc2ccccn2)CCc2ccccn2)cc(CN(CCc2ccccn2)CCc2ccccn2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.57
CYP1A2 P05177 2/20 0.54
CYP3A4 P08684 2/20 0.54
TDP1 Q9NUW8 3/20 0.49
MAPT P10636 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
LIN28A Q9H9Z2 1/20 0.49
OPRM1 P35372 2/20 0.48
OPRD1 P41143 2/20 0.48
OPRK1 P41145 2/20 0.48
CYP2D6 P10635 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
RECQL P46063 1/20 0.47
KDM4E B2RXH2 5/20 0.47
TSHR P16473 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
POLB P06746 1/20 0.47
ATM Q13315 1/20 0.46
ALDH1A1 P00352 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16034589 0.86 APP (0.73) APPCYP1A2CYP3A4TDP1MAPT
SCHEMBL3389096 0.86 CYP2D6 (0.61) APPCYP1A2CYP3A4TDP1MAPT
SCHEMBL4033092 0.80 TDP1 (0.74) CYP1A2CYP3A4TDP1MAPTSMN1; SMN2
SCHEMBL27219673 0.79 TDP1 (0.71) CYP1A2CYP3A4TDP1MAPTSMN1; SMN2
SCHEMBL4961822 0.78 TDP1 (0.63) CYP1A2CYP3A4TDP1MAPTSMN1; SMN2
SCHEMBL4854669 0.77 TDP1 (0.58) CYP1A2CYP3A4TDP1MAPTSMN1; SMN2
SCHEMBL16099570 0.77 CYP1A2 (0.51) CYP1A2CYP3A4TDP1MAPTSMN1; SMN2
SCHEMBL8772399 0.77 TDP1 (0.81) CYP1A2CYP3A4TDP1MAPTSMN1; SMN2
SCHEMBL29980782 0.75 CYP1A2 (0.61) CYP1A2CYP3A4TDP1MAPTSMN1; SMN2
SCHEMBL23495440 0.75 TDP1 (0.78) CYP1A2CYP3A4TDP1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1325777-B1 ABSORBENTS AND PROCESS FOR PRODUCING THE SAME, ABSORBABLE CONSTRUCTS AND ABSORBABLE ARTICLES SANYO CHEMICAL IND LTD (JP) 2010-12-22 EP disclosed
US-7361712-B2 Water absorbing agent, process for its production, and absorbers and absorbent articles made by using the agent SAN-DIA POLYMERS, LTD. (JP) 2008-04-22 US disclosed
US-7087669-B2 Absorbents and process for producing the same, absorbable constructs and absorbable articles SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-08 US disclosed
US-6951911-B2 Cross-linked polymer and process for producing the same, absorptive structure and absorptive article SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2005-10-04 US disclosed
US-20050080194-A1 Water absorbing agent, process for its production, and absorbers and absorbent articles made by using the agent SAN-DIA POLYMERS, LTD. (JP) 2005-04-14 US disclosed
US-20040024104-A1 Absorbents and process for producing the same, absorbable constructs and absorbable articles SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2004-02-05 US disclosed
EP-1325777-A1 ABSORBENTS AND PROCESS FOR PRODUCING THE SAME, ABSORBABLE CONSTRUCTS AND ABSORBABLE ARTICLES SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2003-07-09 EP disclosed
US-20030078349-A1 For use in paper diaper, a physiological napkin, a pad, a paper towel TAGAWA DAISUKE (JP) 2003-04-24 US disclosed
EP-1275669-A1 CROSSLINKED POLYMER, PROCESS FOR PRODUCING THE SAME, ABSORBENT STRUCTURE, AND ABSORBENT ARTICLE SANYO CHEMICAL INDUSTRIES, Ltd. (JP) 2003-01-15 EP disclosed