Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.81 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23495440 | 0.98 | TDP1 (0.78) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL4033092 | 0.96 | TDP1 (0.74) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL27219673 | 0.94 | TDP1 (0.71) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL231092 | 0.90 | TDP1 (1.00) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL29427509 | 0.90 | TDP1 (1.00) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL4961822 | 0.90 | TDP1 (0.63) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL17119746 | 0.88 | TDP1 (0.62) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL10609540 | 0.88 | TDP1 (0.96) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL21973507 | 0.87 | TDP1 (0.72) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL8887822 | 0.86 | TDP1 (0.60) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4706724-A2 | GAS DELIVERY DEVICES | The Regents Of The University Of Michigan (US) | 2026-03-11 | — | — | EP | claimed |
| EP-3609552-B1 | GAS DELIVERY DEVICES | UNIV MICHIGAN REGENTS (US) | 2025-12-10 | — | — | EP | claimed |
| US-11571538-B2 | Gas delivery devices | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-02-07 | — | — | US | claimed |
| EP-4706724-A2 | GAS DELIVERY DEVICES | The Regents Of The University Of Michigan (US) | 2026-03-11 | — | — | EP | disclosed |
| EP-3609552-B1 | GAS DELIVERY DEVICES | UNIV MICHIGAN REGENTS (US) | 2025-12-10 | — | — | EP | disclosed |
| US-12409254-B2 | Catheter insert devices | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2025-09-09 | — | — | US | disclosed |
| CN-114206948-B | catheter insertion device | 密歇根大学董事会 | 2023-11-03 | — | — | CN | disclosed |
| US-11571538-B2 | Gas delivery devices | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-02-07 | — | — | US | disclosed |
| US-20220218880-A1 | CATHETER INSERT DEVICES | UNIV MICHIGAN REGENTS (US) | 2022-07-14 | — | — | US | disclosed |
| EP-3980469-A1 | CATHETER INSERT DEVICES | The Regents of The University of Michigan (US) | 2022-04-13 | — | — | EP | disclosed |
| CN-114206948-A | Catheter insertion device | 密歇根大学董事会 | 2022-03-18 | — | — | CN | disclosed |
| EP-0647158-B1 | METHOD FOR DELIGNIFYING AND BLEACHING A LIGNOCELLULOSE MATERIAL | ELF AQUITAINE (FR) | 1997-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11571538-B2 | Gas delivery devices | NOS2, NOS1, SOD1 | TDP1 4459/4885MAPT 2386/4885SMN1; SMN2 993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.