⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60012 | 1.00 | — | — | |
| SCHEMBL31273801 | 1.00 | HRH3 (0.50) | — | |
| SCHEMBL28826836 | 1.00 | HRH3 (0.50) | — | |
| SCHEMBL19250122 | 0.97 | HRH3 (0.55) | — | |
| SCHEMBL81143 | 0.97 | — | — | |
| SCHEMBL23600074 | 0.97 | HRH3 (0.55) | — | |
| SCHEMBL2745438 | 0.97 | — | — | |
| SCHEMBL14926143 | 0.97 | HRH3 (0.55) | — | |
| Hydrochloric Acid SCHEMBL713346 | 0.97 | — | — | |
| Butane SCHEMBL29156175 | 0.97 | CARM1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854649-A | Gemini quaternary ammonium base type structure directing agent, preparation method thereof, AFX molecular sieve, preparation method thereof and application thereof | 华东理工大学 | 2023-10-10 | — | — | CN | claimed |
| US-7675737-B1 | Low temperature non-aqueous electrolyte | LITHDYNE LLC (US) | 2010-03-09 | — | — | US | claimed |
| US-RE33907-E | Anti-spasmodic agents having a heterocyclic ring | UNITED PHARMACEUTICALS, INC. (US) | 1992-04-28 | — | — | US | claimed |
| US-4857535-A | THIOESTERS | UNITED PHARMACEUTICALS (US) | 1989-08-15 | — | — | US | claimed |
| US-4721783-A | SMOOTH MUSCLES | UNITED PHARMACEUTICALS, INC. (US) | 1988-01-26 | — | — | US | claimed |
| CN-116854649-A | Gemini quaternary ammonium base type structure directing agent, preparation method thereof, AFX molecular sieve, preparation method thereof and application thereof | 华东理工大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-116854649-A | Gemini quaternary ammonium base type structure directing agent, preparation method thereof, AFX molecular sieve, preparation method thereof and application thereof | 华东理工大学 | 2023-10-10 | — | — | CN | disclosed |
| US-20080076760-A1 | 2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION | WAKAMOTO PHARMACEUTICAL CO., LTD (JP) | 2008-03-27 | — | — | US | disclosed |
| EP-1820799-A1 | 2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION | Wakamoto Pharmaceutical Co., Ltd. (JP) | 2007-08-22 | — | — | EP | disclosed |
| EP-0864568-B1 | Agents for treatment of cardiac diseases | KUREHA CHEMICAL IND CO LTD (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-6242445-B1 | CURATIVE EFFECTS FOR CARDIAC AND NEPHRIC DISEASES, ALTHOUGH HAVING LITTLE ACTION ON BLOOD-PRESSURE. | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6211175-B1 | P-AMINOMETHYLBENZOIC ACID DERIVATIVES; CARDIOVASCULAR DISORDERS; NONHYPOTENSIVE | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0807628-B1 | Aromatic compound and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2000-12-20 | — | — | EP | disclosed |
| US-5932575-A | Cardiac diseases improving agents | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| US-5863913-A | ALLEVIATION OF RENAL DYSFUNCTION WITHOUT AFFECTING BLOOD PRESSURE AT A LOW BLOOD CONCENTRATION. | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0864568-A1 | Agents for treatment of cardiac diseases | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| EP-0807628-A1 | Aromatic compound and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-11-19 | — | — | EP | disclosed |
| US-RE33907-E | Anti-spasmodic agents having a heterocyclic ring | UNITED PHARMACEUTICALS, INC. (US) | 1992-04-28 | — | — | US | disclosed |
| US-4857535-A | THIOESTERS | UNITED PHARMACEUTICALS (US) | 1989-08-15 | — | — | US | disclosed |
| US-4721783-A | SMOOTH MUSCLES | UNITED PHARMACEUTICALS, INC. (US) | 1988-01-26 | — | — | US | disclosed |