Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635827 | 0.97 | NPC1 (0.45) | UCHL1NPC1KLK7USP30LMNA | |
| SCHEMBL10201472 | 0.87 | NPC1 (0.48) | UCHL1NPC1KLK7USP30LMNA | |
| SCHEMBL13639050 | 0.85 | NPC1 (0.47) | UCHL1NPC1KLK7USP30LMNA | |
| SCHEMBL10182263 | 0.84 | NPC1 (0.46) | UCHL1NPC1KLK7USP30LMNA | |
| SCHEMBL10121193 | 0.81 | NPC1 (0.51) | UCHL1NPC1KLK7USP30LMNA | |
| SCHEMBL19488759 | 0.81 | NPC1 (0.43) | UCHL1NPC1KLK7USP30LMNA | |
| SCHEMBL692265 | 0.79 | KMT2A (0.48) | UCHL1NPC1KLK7USP30LMNA | |
| SCHEMBL692266 | 0.79 | KMT2A (0.48) | UCHL1NPC1KLK7USP30LMNA | |
| SCHEMBL12159690 | 0.78 | NPC1 (0.50) | UCHL1NPC1KLK7USP30LMNA | |
| SCHEMBL14037470 | 0.76 | NPC1 (0.58) | UCHL1NPC1USP30LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242752-A1 | IMIDAZOLYL BIPHENYL IMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009102325-A1 | IMIDAZOLYL BIPHENYL IMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-20 | — | — | WO | disclosed |