Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10201472 | 0.90 | NPC1 (0.48) | NPC1UCHL1KLK7KMT2AUSP30 | |
| SCHEMBL10182263 | 0.87 | NPC1 (0.46) | NPC1UCHL1KLK7KMT2AUSP30 | |
| SCHEMBL13635827 | 0.86 | NPC1 (0.45) | NPC1UCHL1KLK7KMT2AUSP30 | |
| SCHEMBL3392488 | 0.85 | UCHL1 (0.46) | NPC1UCHL1KLK7KMT2AUSP30 | |
| SCHEMBL10121193 | 0.85 | NPC1 (0.51) | NPC1UCHL1KLK7KMT2AUSP30 | |
| SCHEMBL19488759 | 0.85 | NPC1 (0.43) | NPC1UCHL1KLK7KMT2AUSP30 | |
| SCHEMBL692265 | 0.82 | KMT2A (0.48) | NPC1UCHL1KLK7KMT2AUSP30 | |
| SCHEMBL692266 | 0.82 | KMT2A (0.48) | NPC1UCHL1KLK7KMT2AUSP30 | |
| SCHEMBL12159690 | 0.81 | NPC1 (0.50) | NPC1UCHL1KLK7KMT2AUSP30 | |
| SCHEMBL14037470 | 0.79 | NPC1 (0.58) | NPC1UCHL1KMT2AUSP30LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8303944-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-06 | — | — | US | disclosed |
| US-20090068140-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090068140-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, PYGL, HCCS | NPC1 65/4885UCHL1 405/4885KLK7 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.