Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | VDR | P11473 | 11/20 | 0.38 |
| ▸ | C3AR1 | Q16581 | 5/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259003 | 0.80 | HDAC3 (0.39) | HDAC3HDAC6VDR | |
| SCHEMBL6259000 | 0.80 | HDAC3 (0.39) | HDAC3HDAC6VDRPPARDPPARA | |
| SCHEMBL3392542 | 0.77 | HDAC3 (0.53) | HDAC3HDAC6VDR | |
| SCHEMBL4481031 | 0.76 | HDAC3 (0.38) | HDAC3HDAC6VDRPPARDPPARA | |
| SCHEMBL6438702 | 0.75 | VDR (0.43) | HDAC3HDAC6VDRPPARDPPARA | |
| SCHEMBL6278405 | 0.75 | HDAC3 (0.39) | HDAC3HDAC6VDRPPARDPPARA | |
| SCHEMBL6278407 | 0.75 | HDAC6 (0.39) | HDAC3HDAC6VDR | |
| SCHEMBL6440884 | 0.73 | HDAC6 (0.40) | HDAC3HDAC6VDR | |
| SCHEMBL3395489 | 0.73 | HDAC6 (0.41) | HDAC3HDAC6VDR | |
| SCHEMBL6466925 | 0.72 | HDAC6 (0.43) | HDAC3HDAC6VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2184281-A1 | Phenyl-thiophene type vitamin D receptor modulators | Eli Lilly & Company (US) | 2010-05-12 | — | — | EP | disclosed |