⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5716960 | 0.80 | ALDH1A1 (0.33) | — | |
| SCHEMBL17123851 | 0.79 | — | — | |
| SCHEMBL8386029 | 0.77 | CYP2C19 (0.50) | — | |
| SCHEMBL27692282 | 0.77 | — | — | |
| SCHEMBL8011919 | 0.77 | — | — | |
| SCHEMBL4306877 | 0.77 | — | — | |
| SCHEMBL27733484 | 0.77 | — | — | |
| SCHEMBL10460963 | 0.75 | TSHR (0.33) | — | |
| SCHEMBL12168354 | 0.75 | TSHR (0.33) | — | |
| SCHEMBL11797613 | 0.75 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2157095-A2 | Synthesis of beta-L-2-Deoxy nucleosides | Novartis Ag (CH) | 2010-02-24 | — | — | EP | disclosed |
| EP-1639121-A4 | SYNTHESIS OF BETA -L-2-DEOXY NUCLEOSIDES | IDENIX CAYMAN LTD (KY) | 2008-04-16 | — | — | EP | disclosed |
| EP-1639121-A2 | SYNTHESIS OF BETA -L-2-DEOXY NUCLEOSIDES | Idenix (Cayman) Limited (KY) | 2006-03-29 | — | — | EP | disclosed |
| US-20050059632-A1 | Synthesis of beta-L-2'-deoxy nucleosides | NOVARTIS AG (CH) | 2005-03-17 | — | — | US | disclosed |
| WO-2005003374-A2 | SYNTHESIS OF β-L-2-DEOXY NUCLEOSIDES | IDENIX (CAYMAN) LIMITED (KY) | 2005-01-13 | — | — | WO | disclosed |
| EP-1326619-A2 | PYRROLIDINE MODULATORS OF CCR5 CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002034716-A2 | PYRROLIDINE MODULATORS OF CCR5 CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2002-05-02 | — | — | WO | disclosed |
| US-5364970-A | Rhodium catalyst, selectivity, preparation of methyl alpha-formylisobutyrate | SHELL OIL COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0204736-B1 | PROCESS FOR THE PREPARATION OF BENZENE DERIVATIVES | L. GIVAUDAN & CIE Société Anonyme (CH) | 1989-07-26 | — | — | EP | disclosed |