Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.54 |
| ▸ | MAOB | P27338 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CALML3 | P27482 | 1/20 | 0.41 |
| ▸ | SDHA | P31040 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 6/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394931 | 0.89 | MAOB (0.49) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3394934 | 0.79 | MAOB (0.41) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3390779 | 0.78 | MAOB (0.55) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3397391 | 0.77 | MAOB (0.55) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3394843 | 0.76 | MAOB (0.55) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3396973 | 0.76 | MAOA (0.60) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3398585 | 0.76 | MAOB (0.52) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3395634 | 0.75 | MAOB (0.55) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3394910 | 0.75 | MAOB (0.54) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3394992 | 0.74 | MAOB (0.55) | MAOAMAOBLMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234390-A1 | NOVEL COMPOUND AND THEIR USE | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234390-A1 | NOVEL COMPOUND AND THEIR USE | HTRA1, PRSS1, PRNP | MAOA 2174/4885MAOB 2054/4885LMNA 2167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.