Butyric Acid

Butyric Acid

SCHEMBL339305

CCCC(=O)O.CCCC(=O)O.CCCC(=O)O.CCCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 3/20 1.00
HDAC3 O15379 2/20 1.00
HDAC1 Q13547 2/20 1.00
HDAC2 Q92769 2/20 1.00
HDAC8 Q9BY41 2/20 1.00
AKR1B1 P15121 1/20 0.61
GPR84 Q9NQS5 7/20 0.58
PPARG P37231 7/20 0.58
PPARD Q03181 7/20 0.58
PPARA Q07869 7/20 0.58
HDAC11 Q96DB2 5/20 0.58
TSHR P16473 5/20 0.58
PTPN1 P18031 3/20 0.58
ALDH1A1 P00352 2/20 0.58
TLR2 O60603 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
FABP4 P15090 2/20 0.58
SLC22A6 Q4U2R8 1/20 0.58
SLC22A8 Q8TCC7 1/20 0.58
MEN1 O00255 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyric Acid SCHEMBL1330379 1.00
Butyric Acid SCHEMBL991717 1.00 FFAR3 (1.00) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL320515 1.00 FFAR3 (1.00) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL4446516 1.00 FFAR3 (1.00) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL1332215 1.00
Butyric Acid SCHEMBL5703921 1.00 FFAR3 (1.00) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL8458708 1.00 FFAR3 (1.00) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL8457839 1.00 FFAR3 (1.00) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL20678495 1.00
Butyric Acid SCHEMBL2503 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3368600-B1 WATER-BASED COATING COMPOSITIONS SUN CHEMICAL CORP (US) 2020-06-10 EP claimed
US-20140080769-A1 SUBSTRATE REDUCTION THERAPY THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) 2014-03-20 US claimed
EP-1808467-B1 Liquid silicone rubber coating composition, curtain airbag and making method SHINETSU CHEMICAL CO (JP) 2014-03-05 EP claimed
EP-1968991-B9 BIS-PLATINUM COMPLEXES WITH ANTITUMOR ACTIVITY CELL THERAPEUTICS INC SEDE SECONDARIA (IT) 2012-08-08 EP claimed
EP-1968991-B1 BIS-PLATINUM COMPLEXES WITH ANTITUMOR ACTIVITY CELL THERAPEUTICS INC SEDE SECONDARIA (IT) 2012-01-18 EP claimed
US-20100204162-A1 SUBSTRATE REDUCTION THERAPY THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2010-08-12 US claimed
EP-2182936-A2 SUBSTRATE REDUCTION THERAPY THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) 2010-05-12 EP claimed
US-20100022620-A1 EPITOPE REDUCTION THERAPY ISIS INNOVATION LIMITED (GB) 2010-01-28 US claimed
WO-2009141627-A1 TREATING NIEMANN-PICK DISEASE TYPE C AND RELATED DISORDERS BY ELEVATING INTRACELLULAR CALCIUM ISIS INNOVATION LIMITED (GB) 2009-11-26 WO claimed
US-7612093-B2 Compositions of treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds in combination therapy UNITED THERAPEUTICS CORPORATION (US) 2009-11-03 US claimed
US-5798366-A Method for treatment of CNS-involved lysosomal storage diseases MONSANTO COMPANY (US) 1998-08-25 US claimed
WO-1998035685-A1 USE OF N-SUBSTITUTED-1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL COMPOUNDS IN COMBINATION THERAPY FOR TREATING HEPATITIS VIRUS INFECTIONS G.D. SEARLE AND CO. (US) 1998-08-20 WO claimed
WO-1998030219-A1 METHOD FOR TREATMENT OF CNS-INVOLVED LYSOSOMAL STORAGE DISEASES MONSANTO COMPANY (US) 1998-07-16 WO claimed
EP-0384366-B1 Photosensitive recording element BASF AG (DE) 1995-02-15 EP claimed
EP-0367748-B1 Novel antiviral compounds SEARLE & CO (US) 1995-01-25 EP claimed
US-5310745-A Acylated derivatives of 1,5-dideoxy-1,5-imino-D-glucitol, AIDS G. D. SEARLE & CO. (US) 1994-05-10 US claimed
US-5003072-A Viricides G. D. SEARLE & CO. (US) 1991-03-26 US claimed
EP-0367748-A2 Novel antiviral compounds G.D. SEARLE & COMPANY (US) 1990-05-09 EP claimed
US-4407821-A LINOLENIC ACID OR ESTER, TRIGLYCERIDES ROUSSEL UCLAF (FR) 1983-10-04 US claimed
US-4009199-A IMPREGNATION OF SILICA GEL CATALYST WITH ALUMINUM-TITANIUM-ZINC-TIN COMPOUNDS CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DT) 1977-02-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204162-A1 SUBSTRATE REDUCTION THERAPY GBA1, SPTLC2, NPC1L1 FFAR3 1029/4885HDAC3 1332/4885HDAC1 1089/4885
US-20140080769-A1 SUBSTRATE REDUCTION THERAPY GBA1, SPTLC2, NPC1L1 FFAR3 1029/4885HDAC3 1332/4885HDAC1 1089/4885
US-20100022620-A1 EPITOPE REDUCTION THERAPY UGCG, GBA1, ENGASE FFAR3 1001/4885HDAC3 1504/4885HDAC1 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.