Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 5/20 | 0.32 |
| ▸ | MINK1 | Q8N4C8 | 5/20 | 0.32 |
| ▸ | PRKD2 | Q9BZL6 | 4/20 | 0.32 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 5/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.31 |
| ▸ | TAOK1 | Q7L7X3 | 4/20 | 0.31 |
| ▸ | GSK3B | P49841 | 3/20 | 0.31 |
| ▸ | CSNK1G3 | Q9Y6M4 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14632155 | 0.86 | EGLN2 (0.39) | — | |
| SCHEMBL3388535 | 0.81 | MAPK14 (0.35) | GRM5MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL3395698 | 0.74 | PHGDH (0.38) | — | |
| SCHEMBL15879853 | 0.74 | TP53 (0.36) | SLC34A1MAPK14 | |
| SCHEMBL1691390 | 0.71 | DPP4 (0.39) | MAPK14MAP4K4CSNK1DMINK1PRKD2 | |
| SCHEMBL15879650 | 0.69 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL14632043 | 0.69 | FDPS (0.33) | MAPK14CNR1 | |
| SCHEMBL3395134 | 0.69 | MAPK14 (0.35) | SLC34A1MAPK14MAP4K4MAPK9CSNK1D | |
| SCHEMBL3391489 | 0.68 | DPP4 (0.50) | GRM5PRKD3PRKCG | |
| SCHEMBL3433131 | 0.65 | MDM2 (0.41) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239905-A1 | IMIDAZOPYRIDINE COMPOUNDS | BIOVITRUM AB (PUBL) (SE) | 2015-08-27 | — | — | US | disclosed |
| US-20140206662-A1 | Imidazopyridine Compounds | PROXIMAGEN LTD. (GB) | 2014-07-24 | — | — | US | disclosed |
| EP-2376490-B1 | IMIDAZOPYRIDINE COMPOUNDS | PROXIMAGEN LTD (GB) | 2013-01-23 | — | — | EP | disclosed |
| WO-2010064020-A1 | IMIDAZOPYRIDINE COMPOUNDS | PROXIMAGEN LTD. (GB) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239905-A1 | IMIDAZOPYRIDINE COMPOUNDS | SSB, MIF, IDO1 | SLC34A1 505/4885GRM5 4367/4885MAPK14 3550/4885 |
| US-20140206662-A1 | Imidazopyridine Compounds | SSB, NFKBIA, TPMT | SLC34A1 662/4885GRM5 4509/4885MAPK14 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.