SCHEMBL3393280

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3395796	0.90	IKBKB (0.47)	IKBKBCHUKJAK2BTKPARP1
	SCHEMBL3391160	0.87	CHUK (0.48)	IKBKBCHUKBTKAAK1
	SCHEMBL27698220	0.86	IKBKB (0.45)	IKBKBCHUKJAK2BTKCHEK1
	SCHEMBL3391461	0.84	IKBKB (0.64)	IKBKBCHUKBTKCSF1R
	SCHEMBL14365537	0.84	BTK (0.49)	IKBKBCHUKJAK2BTKAAK1
	SCHEMBL3391348	0.84	IKBKB (0.51)	IKBKBCHUKBTKCHEK1PARP1
	SCHEMBL3393228	0.83	JAK2 (0.46)	JAK2BTKAAK1PARP1USP30
	Hydrochloric Acid SCHEMBL3395054	0.83	IKBKB (0.63)	IKBKBCHUKBTKCSF1R
	SCHEMBL3393266	0.80	MKNK1 (0.53)	IKBKBCHUKBTKCHEK1DYRK1A
	SCHEMBL3395738	0.79	BTK (0.43)	IKBKBCHUKJAK2BTKAAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.