Sugi Predict

Sugi Predict / Targets / IKBKG

IKBKG

NF-kappa-B essential modulator · Q9Y6K9 · IKBKG on Sugi Atlas →

3,156 patent compounds predicted against IKBKG, 1,911 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL938293 SCHEMBL938293 0.57 13/20
SCHEMBL937376 SCHEMBL937376 0.56 12/20
SCHEMBL2196232 SCHEMBL2196232 0.54 12/20
SCHEMBL5070960 SCHEMBL5070960 0.64 10/20
SCHEMBL4000808 SCHEMBL4000808 0.57 10/20
SCHEMBL4000789 SCHEMBL4000789 0.50 10/20
SCHEMBL4987511 SCHEMBL4987511 0.50 10/20
SCHEMBL4146248 SCHEMBL4146248 0.56 9/20
SCHEMBL4008028 SCHEMBL4008028 0.56 9/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL3961613) 0.51 9/20
SCHEMBL3303267 SCHEMBL3303267 0.51 9/20
SCHEMBL2972101 SCHEMBL2972101 0.50 9/20
SCHEMBL3962260 SCHEMBL3962260 0.50 9/20
SCHEMBL3969609 SCHEMBL3969609 0.50 9/20
SCHEMBL4492934 SCHEMBL4492934 0.50 9/20
SCHEMBL4492936 SCHEMBL4492936 0.50 9/20
SCHEMBL4492941 SCHEMBL4492941 0.50 9/20
SCHEMBL4000785 SCHEMBL4000785 0.49 9/20
SCHEMBL4003596 SCHEMBL4003596 0.49 9/20
SCHEMBL3470408 SCHEMBL3470408 0.47 9/20

Clinical trials — most relevant to IKBKG by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Salsalate Therapy to Reduce Insulin Resistance and Cardiovascular Risk PHASE2/PHASE3COMPLETED
Bradykinin Receptor Antagonism During Cardiopulmonary Bypass PHASE2/PHASE3COMPLETED
The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room PHASE2/PHASE3COMPLETED
Study of Carfilzomib With Irinotecan in Irinotecan-Sensitive Malignancies and Small Cell Lung Cancer Patients PHASE1/PHASE2COMPLETED
Effect of Salicylate on Glucose Metabolism in Insulin Resistance States PHASE1/PHASE2COMPLETED
Effects of Gum Arabic on Metabolic Syndrome Parameters in Postmenopausal Women PHASE2COMPLETED
Safety, Efficacy and Pharmacokinetic Between Capecitabine and Exisulind in Metastatic Breast Cancer Patients PHASE1/PHASE2COMPLETED
Isoflavones and Acute-phase Response in Chronic Renal Failure PHASE2COMPLETED
TNFSF11 Inhibition and Fertility: a Prospective Study PHASE2COMPLETED
Ibrutinib, Obinutuzumab and Venetoclax for Patients With Chronic Lymphocytic Leukemia PHASE2COMPLETED
Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma PHASE2COMPLETED
Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablation PHASE2ACTIVE_NOT_RECRUITING
Efficacy of Teriparatide in Diabetic Inactive Charcot Neuroarthropathy of Foot PHASE2COMPLETED
Sodium Bicarbonate in Cardiac Surgery PHASE2COMPLETED
Impact of Colchicine and Low-dose Naltrexone on COVID-19 PHASE2COMPLETED
Efficacy of Amlexanox vs. Placebo in Type 2 Diabetic Patients PHASE2COMPLETED
Study of Irinotecan and Bortezomib in Children With Recurrent/Refractory Neuroblastoma PHASE1COMPLETED
IKBKB Gene Polymorphism (Single Nucleotide Polymorphism) (SNP) in Psoriatic and Psoriatic Arthritis Patients nanCOMPLETED
MicroRNAs and Cytokines in Peri-Implantitis Tissue nanUNKNOWN
Novel Biomarkers in Inflammatory Bowel Disease nanCOMPLETED
Diagnosis of Inflammatory Bowel Disease nanNOT_YET_RECRUITING
Early Regenerative Intervention for Post-Traumatic Osteoarthritis nanUNKNOWN
Magnesium and Vitamin D Combination for Post-COVID Syndrome nanCOMPLETED
Card14gene (rs34367357 ) Polymorphism in Egyptian Psoriatic and Psoriatic Arthritis Patient nanRECRUITING
Possible Diagnostic Protein Markers in Schistosoma Related Bladder Diseases. nanNOT_YET_RECRUITING
Role of NFKBIA and PTPN22 Genes Polymorphism in Acute Rejection Susceptibility After Living Donor Liver Transplantation in Egyptian Patients. nanCOMPLETED
Oral Glutamine in Cardiopulmonary Bypass nanCOMPLETED
Post-surgery Systemic Inflammation and Neuro-immune Interactions nanCOMPLETED
The Pathophysiology of Bortezomib Induced Peripheral Neuropathy nanUNKNOWN
Evaluation of the Effect of Alpha Lipoic Acid on Radiation Induced Dermatitis in Breast Cancer Patients nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a IKBKG binder may also engage these)

ProteinNameSimilarity
Q6TMG5 — 1.000 Q6TMG5 →
A9QT41 — 1.000 A9QT41 →
Q95KU9 — 1.000 Q95KU9 →
O88522 — 1.000 O88522 →
Q8VDC1 — 1.000 Q8VDC1 →
Q9ULE4 — 0.999 Q9ULE4 →
Q29RS0 — 0.998 Q29RS0 →
B9V5F5 — 0.998 B9V5F5 →
Q8K3K8 — 0.998 Q8K3K8 →
Q7YS99 — 0.997 Q7YS99 →
Q2TAC2 — 0.997 Q2TAC2 →
Q8N998 — 0.997 Q8N998 →
A6QNP9 — 0.997 A6QNP9 →
Q502I3 — 0.996 Q502I3 →
Q96ST8 — 0.996 Q96ST8 →
Q8CJ40 — 0.996 Q8CJ40 →
A0JNT9 — 0.996 A0JNT9 →
Q8N283 — 0.995 Q8N283 →
Q9CZX2 — 0.995 Q9CZX2 →
Q95JI9 — 0.995 Q95JI9 →
Q0KK56 — 0.995 Q0KK56 →
Q86SQ7 — 0.995 Q86SQ7 →
Q9DEX1 — 0.995 Q9DEX1 →
Q8R5M4 — 0.995 Q8R5M4 →
Q9WVQ0 — 0.995 Q9WVQ0 →
Q9H257 — 0.995 Q9H257 →
Q92805 — 0.994 Q92805 →
NUMA1 Nuclear mitotic apparatus protein 1 0.994 landscape →
Q9CW79 — 0.994 Q9CW79 →
Q8CHW5 — 0.994 Q8CHW5 →