Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 5/20 | 0.63 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.63 |
| ▸ | F2 | P00734 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272510 | 0.88 | NR1H2 (0.76) | NR1H2NR1H3F2KMT2AMAPT | |
| SCHEMBL13426481 | 0.80 | NR1H2 (0.52) | NR1H2NR1H3F2KMT2AMAPT | |
| SCHEMBL10476799 | 0.77 | NR1H2 (1.00) | NR1H2NR1H3F2KMT2AMAPT | |
| SCHEMBL5275814 | 0.77 | NR1H2 (0.49) | NR1H2NR1H3F2KMT2AMAPT | |
| SCHEMBL17570200 | 0.76 | NR1H2 (0.97) | NR1H2NR1H3F2KMT2AMAPT | |
| SCHEMBL3432544 | 0.75 | NR1H2 (0.50) | NR1H2NR1H3F2KMT2AMAPT | |
| SCHEMBL424645 | 0.74 | TRPV1 (0.53) | NR1H2NR1H3KMT2AHPGDALDH1A1 | |
| SCHEMBL17570201 | 0.73 | NR1H2 (0.85) | NR1H2NR1H3F2KMT2AMAPT | |
| SCHEMBL16202035 | 0.73 | NR1H3 (0.71) | NR1H2NR1H3KMT2AMAPTCYP1A2 | |
| SCHEMBL14736604 | 0.72 | TSHR (0.53) | NR1H2NR1H3KMT2AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |