Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7639922 | 0.80 | — | — | |
| SCHEMBL788281 | 0.73 | — | — | |
| Crotonic Acid SCHEMBL28625666 | 0.72 | — | — | |
| SCHEMBL28726001 | 0.72 | TSHR (0.50) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL3394986 | 0.71 | — | — | |
| SCHEMBL11636633 | 0.71 | — | — | |
| SCHEMBL1533442 | 0.71 | — | — | |
| SCHEMBL458329 | 0.71 | — | — | |
| SCHEMBL3363074 | 0.71 | — | — | |
| SCHEMBL23829583 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185692-B1 | MONOLAYER AND ELECTRODE FOR DETECTING A LABEL-BEARING TARGET AND METHOD OF USE THEREOF | UNIV NORTH CAROLINA (US) | 2005-12-07 | — | — | EP | claimed |
| JP-2002542794-A | — | — | 2002-12-17 | — | — | JP | claimed |
| US-6387625-B1 | ELECTRODE HAVING SUBSTRATE WITH ELECTROCONDUCTIVE WORKING SURFACE; SURFACE HAS NONCONDUCTIVE SELF-ASSEMBLED MONOLAYER WITH PHOSPHONATE GROUP; A TRANSITION METAL COMPLEX IS USED TO TRANSFER ELECTRONS FROM REACTANT TO SURFACE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2002-05-14 | — | — | US | claimed |
| EP-1185692-A1 | MONOLAYER AND ELECTRODE FOR DETECTING A LABEL-BEARING TARGET AND METHOD OF USE THEREOF | The University of North Carolina at Chapel Hill (US) | 2002-03-13 | — | — | EP | claimed |
| WO-2000065099-A1 | MONOLAYER AND ELECTRODE FOR DETECTING A LABEL-BEARING TARGET AND METHOD OF USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-11-02 | — | — | WO | claimed |
| US-6127127-A | Monolayer and electrode for detecting a label-bearing target and method of use thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-10-03 | — | — | US | claimed |
| CN-109790259-A | Copolymer and the medical material for using it | 东丽株式会社 | 2019-05-21 | — | — | CN | disclosed |
| CN-107405431-A | Antithrombotic metal material | 东丽株式会社 | 2017-11-28 | — | — | CN | disclosed |
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| EP-1509537-B9 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES INC (US) | 2007-11-14 | — | — | EP | disclosed |
| EP-1509537-B1 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES INC (US) | 2007-07-18 | — | — | EP | disclosed |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |
| EP-1711617-A1 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTICS COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2006-10-18 | — | — | EP | disclosed |
| US-20020037530-A1 | Detection of binding reactions using labels detected by mediated catalytic electrochemistry | STEWART DAVID H (US) | 2002-03-28 | — | — | US | disclosed |
| EP-1185692-A1 | MONOLAYER AND ELECTRODE FOR DETECTING A LABEL-BEARING TARGET AND METHOD OF USE THEREOF | The University of North Carolina at Chapel Hill (US) | 2002-03-13 | — | — | EP | disclosed |
| US-6346387-B1 | CONTACTING IMMOBILIZED BINDER WITH TEST SAMPLE TO COMPLEX TARGET; CONTACTING WITH SECOND BINDER HAVING EXOGENOUS OR ENDOGENOUS LABEL; OXIDATION WITH TRANSITION METAL COMPOUND; DETECTING OXIDATION-REDUCTION REACTION | XANTHON, INC. | 2002-02-12 | — | — | US | disclosed |
| WO-2000065099-A1 | MONOLAYER AND ELECTRODE FOR DETECTING A LABEL-BEARING TARGET AND METHOD OF USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-11-02 | — | — | WO | disclosed |
| US-6127127-A | Monolayer and electrode for detecting a label-bearing target and method of use thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-10-03 | — | — | US | disclosed |
| WO-1995006751-A9 | METHODS FOR ISOLATION OF MOST ABUNDANT OLIGONUCLEOTIDES FROM COMPLEX MIXTURES | — | 1995-04-20 | — | — | WO | disclosed |
| WO-1995006751-A1 | METHODS FOR ISOLATION OF MOST ABUNDANT OLIGONUCLEOTIDES FROM COMPLEX MIXTURES | PHARMAGENICS, INC. (US) | 1995-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | PPA1, PNP, PPME1 | TSHR 4782/4885GABRR1 4016/4885GABRR2 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.