Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393447 | 0.81 | CYP2D6 (0.33) | CYP2D6APLNRCA1CA2CA7 | |
| SCHEMBL2080034 | 0.77 | CYP2D6 (0.40) | CYP2D6APLNRCA1CA2CA7 | |
| SCHEMBL303916 | 0.75 | TSHR (0.37) | — | |
| SCHEMBL29004730 | 0.72 | CYP2D6 (0.37) | CYP2D6APLNRCA1CA2CA7 | |
| SCHEMBL14879622 | 0.72 | CYP2D6 (0.37) | CYP2D6APLNRCA1CA2CA7 | |
| SCHEMBL28626116 | 0.72 | GRIN2D (0.39) | CYP2D6APLNRCA1CA2CA7 | |
| SCHEMBL28841425 | 0.72 | TSHR (0.34) | — | |
| SCHEMBL9391923 | 0.72 | GRIN2D (0.39) | CYP2D6APLNRCA1CA2CA7 | |
| SCHEMBL29102071 | 0.72 | TSHR (0.34) | — | |
| SCHEMBL1205245 | 0.70 | APLNR (0.33) | CYP2D6APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673113-B1 | IMPLANTS WITH ATTACHED SILYLATED THERAPEUTIC AGENTS | SMART TECH LP (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20060286140-A1 | Implants with attached silylated therapeutic agents | SMART TECH LP | 2006-12-21 | — | — | US | disclosed |
| EP-1673113-A2 | IMPLANTS WITH ATTACHED SILYLATED THERAPEUTIC AGENTS | Wickstrom, Eric (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005027990-A2 | IMPLANTS WITH ATTACHED SILYLATED THERAPEUTIC AGENTS | UNIV JEFFERSON (US) | 2005-03-31 | — | — | WO | disclosed |