Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1262187 | 0.99 | DPP4 (0.37) | DPP4HTR2CHTR2AHTR2BSMN1; SMN2 | |
| SCHEMBL3421612 | 0.85 | DPP4 (0.36) | DPP4HTR2CHTR2AHTR2BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1262905 | 0.84 | DPP4 (0.36) | DPP4HTR2CHTR2AHTR2BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1262608 | 0.81 | HTR2A (0.36) | HTR2CHTR2AHTR2BSMN1; SMN2L3MBTL1 | |
| SCHEMBL3389240 | 0.80 | HTR2A (0.37) | HTR2CHTR2AHTR2BSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1262759 | 0.79 | HTR2A (0.36) | HTR2CHTR2AHTR2BSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1262892 | 0.75 | HTR2A (0.34) | HTR2CHTR2AHTR2B | |
| SCHEMBL1970467 | 0.74 | HTR2A (0.36) | HTR2CHTR2AHTR2BSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1262763 | 0.73 | HTR2A (0.35) | HTR2CHTR2AHTR2BSMN1; SMN2L3MBTL1 | |
| SCHEMBL1967719 | 0.72 | HTR2A (0.34) | DPP4HTR2CHTR2AHTR2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863812-B1 | DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD (KR) | 2010-07-14 | — | — | EP | disclosed |
| EP-1863812-A4 | DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD (KR) | 2009-06-24 | — | — | EP | disclosed |
| EP-1863812-A1 | DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG Life Sciences Ltd. (KR) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006104356-A1 | DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES, LTD. (KR) | 2006-10-05 | — | — | WO | disclosed |