Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392938 | 0.91 | KCNH2 (0.54) | KCNH2DYRK1AMAPTCDK2ALDH1A1 | |
| SCHEMBL13425792 | 0.90 | KCNH2 (0.61) | KCNH2DYRK1ATNIKHRH2HRH1 | |
| SCHEMBL13425748 | 0.88 | KCNH2 (0.53) | KCNH2MAPTPKMHRH2HRH1 | |
| SCHEMBL3432958 | 0.87 | KCNH2 (0.60) | KCNH2DYRK1ATNIKIDH1SCN9A | |
| SCHEMBL3396018 | 0.86 | KCNH2 (0.58) | KCNH2DYRK1ATNIKHRH2HRH1 | |
| SCHEMBL13425739 | 0.86 | KCNH2 (0.60) | KCNH2DYRK1ATNIKHRH2HRH1 | |
| SCHEMBL13425780 | 0.86 | KCNH2 (0.61) | KCNH2DYRK1AMAPTNPC1POLB | |
| SCHEMBL13425763 | 0.86 | KCNH2 (0.60) | KCNH2POLBTNIKALDH1A1KDM4E | |
| SCHEMBL13425820 | 0.86 | KCNH2 (0.40) | KCNH2DYRK1AMAPTNPC1PKM | |
| SCHEMBL3395952 | 0.86 | KCNH2 (0.56) | KCNH2DYRK1AMAPTNPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |