Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | EIF4E | P06730 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393631 | 0.86 | KCNH2 (0.54) | KCNH2KMT2AMAPTMEN1RAB9A | |
| SCHEMBL13425748 | 0.86 | KCNH2 (0.53) | KCNH2MAPTLMNAPKMLRRK2 | |
| SCHEMBL3392938 | 0.86 | KCNH2 (0.54) | KCNH2MAPTLMNAHPGDALDH1A1 | |
| SCHEMBL13425826 | 0.85 | KCNH2 (0.64) | KCNH2KMT2AMAPTMEN1RAB9A | |
| SCHEMBL13426245 | 0.85 | KCNH2 (0.60) | KCNH2MAPTLMNAHPGDALDH1A1 | |
| SCHEMBL13426224 | 0.85 | KCNH2 (0.60) | KCNH2MAPTLMNAHPGDALDH1A1 | |
| SCHEMBL3394278 | 0.85 | KCNH2 (0.60) | KCNH2KMT2AMAPTMEN1RAB9A | |
| SCHEMBL13426154 | 0.85 | KCNH2 (0.68) | KCNH2MAPTLMNAHPGDALDH1A1 | |
| SCHEMBL13426280 | 0.83 | KCNH2 (0.58) | KCNH2KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL13425792 | 0.83 | KCNH2 (0.61) | KCNH2LMNAHPGDALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |