Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 16/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393947 | 1.00 | CCR5 (0.42) | CCR5KDM1AMAOBKMT2ATACR1 | |
| Hydrochloric Acid SCHEMBL3391641 | 0.99 | CCR5 (0.41) | CCR5KDM1AMAOBKMT2ATACR1 | |
| Hydrochloric Acid SCHEMBL3391645 | 0.99 | CCR5 (0.41) | CCR5KDM1AMAOBKMT2ATACR1 | |
| SCHEMBL3394475 | 0.92 | CCR5 (0.43) | CCR5KDM1AMAOBKMT2A | |
| SCHEMBL3394478 | 0.92 | CCR5 (0.43) | CCR5KDM1AMAOBKMT2A | |
| Hydrochloric Acid SCHEMBL3394820 | 0.91 | CCR5 (0.43) | CCR5KDM1AMAOBKMT2A | |
| Hydrochloric Acid SCHEMBL3394816 | 0.91 | CCR5 (0.43) | CCR5KDM1AMAOBKMT2A | |
| SCHEMBL3391412 | 0.89 | CCR5 (0.43) | CCR5KDM1AMAOBKMT2A | |
| SCHEMBL3391418 | 0.89 | CCR5 (0.43) | CCR5KDM1AMAOBKMT2A | |
| Hydrochloric Acid SCHEMBL3391667 | 0.89 | CCR5 (0.43) | CCR5KDM1AMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709642-B2 | Spirohydantoin compounds and methods for the modulation of chemokine receptor activity | VIROCHEM PHARMA, INC. (CA) | 2010-05-04 | — | — | US | claimed |