Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | BCR | P11274 | 1/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18648519 | 1.00 | TUBB1 (0.59) | TUBB1ABL1BCRCYP1A1PTGS1 | |
| SCHEMBL10281431 | 0.86 | PTGS1 (0.74) | TUBB1ABL1BCRCYP1A1PTGS1 | |
| SCHEMBL15633028 | 0.85 | TUBB1 (0.78) | TUBB1ABL1BCRCYP1A1PTGS1 | |
| SCHEMBL30609589 | 0.85 | TUBB1 (0.78) | TUBB1ABL1BCRCYP1A1PTGS1 | |
| SCHEMBL15633027 | 0.85 | TUBB1 (0.78) | TUBB1ABL1BCRCYP1A1PTGS1 | |
| SCHEMBL14363441 | 0.84 | CYP1A1 (0.73) | TUBB1CYP1A1PTGS1PTGS2APP | |
| SCHEMBL20223710 | 0.83 | TUBB1 (0.68) | TUBB1CYP1A1PTGS1PTGS2APP | |
| SCHEMBL27305906 | 0.81 | LCK (0.70) | TUBB1ABL1BCRPTGS1PTGS2 | |
| SCHEMBL5315834 | 0.79 | ABL1 (0.67) | TUBB1ABL1BCRCYP1A1PTGS1 | |
| SCHEMBL21980865 | 0.78 | TUBB1 (0.71) | TUBB1ABL1BCRCYP1A1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245019-A1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009103626-A1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-08-27 | — | — | WO | disclosed |