SCHEMBL5315834

SCHEMBL5315834

COc1cc(C=Cc2cccc(O)c2)cc(OC)c1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 2/20 0.67
BCR P11274 2/20 0.67
TUBB1 Q9H4B7 4/20 0.65
LCK P06239 2/20 0.63
PTGS1 P23219 2/20 0.59
PTGS2 P35354 2/20 0.59
CYP1A1 P04798 2/20 0.59
TTR P02766 1/20 0.57
CYP1A2 P05177 2/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2B6 P20813 1/20 0.54
TUBB4A P04350 2/20 0.54
TUBB P07437 2/20 0.54
TUBA3C P0DPH7 2/20 0.54
TUBA1B P68363 2/20 0.54
TUBA4A P68366 2/20 0.54
TUBB4B P68371 2/20 0.54
TUBB3 Q13509 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21980876 0.88 TUBB1 (0.71) ABL1BCRTUBB1LCKPTGS1
SCHEMBL21980865 0.88 TUBB1 (0.71) ABL1BCRTUBB1LCKPTGS1
SCHEMBL2927389 0.85 TUBB1 (0.70) ABL1BCRTUBB1PTGS1PTGS2
SCHEMBL2927384 0.85 TUBB1 (0.70) ABL1BCRTUBB1PTGS1PTGS2
SCHEMBL17843663 0.84 ABL1 (0.80) ABL1BCRTUBB1PTGS1PTGS2
SCHEMBL16372856 0.84 ABL1 (0.80) ABL1BCRTUBB1PTGS1PTGS2
SCHEMBL20719887 0.83 ABL1 (0.71) ABL1BCRTUBB1LCKPTGS1
SCHEMBL14000544 0.83 TUBB1 (0.76) ABL1BCRTUBB1PTGS1PTGS2
SCHEMBL6844172 0.83 TUBB1 (0.76) ABL1BCRTUBB1PTGS1PTGS2
SCHEMBL17938777 0.81 MAPT (0.69) ABL1BCRTUBB1PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070276172-A1 Single step microwave induced process for the preparation of substituted stilbenes and its analogs COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-11-29 US disclosed
WO-2007110883-A1 A SINGLE STEP MICROWAVE INDUCED PROCESS FOR THE PREPARATION OF SUBSTITUTED STILBENES AND ITS ANALOGS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070276172-A1 Single step microwave induced process for the preparation of substituted stilbenes and its analogs HRH3, HPD, TET2 ABL1 1030/4885BCR 4016/4885TUBB1 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.