Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 9/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2678166 | 0.95 | SCD (0.48) | SCDCHRNA7HTR3ACHRNB4CHRNA3 | |
| SCHEMBL3390808 | 0.86 | CHRNA7 (0.50) | SCDCHRNA7HTR3ACHRNB4CHRNA3 | |
| SCHEMBL928191 | 0.86 | CHRNA7 (0.68) | CHRNA7HTR3ACHRNB4CHRNA3 | |
| SCHEMBL3393866 | 0.84 | CHRNA7 (0.49) | SCDCHRNA7HTR3ACHRNB4CHRNA3 | |
| SCHEMBL3390767 | 0.84 | CHRNA7 (0.48) | SCDCHRNA7HTR3ACHRNB4CHRNA3 | |
| SCHEMBL2677317 | 0.81 | ACACB (0.49) | SCDCHRNA7HTR3ACHRNB4CHRNA3 | |
| SCHEMBL2677567 | 0.81 | CHRNA7 (0.43) | SCDCHRNA7HTR3ACHRNB4CHRNA3 | |
| SCHEMBL2678491 | 0.81 | SCD (0.48) | SCDCHRNA7HTR3ACHRNB4CHRNA3 | |
| SCHEMBL2676639 | 0.81 | CHRNA7 (0.64) | CHRNA7HTR3ACHRNB4CHRNA3 | |
| SCHEMBL1449402 | 0.81 | CHRNA7 (0.64) | CHRNA7HTR3ACHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805183-B1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH AS (DK) | 2010-12-29 | — | — | EP | claimed |
| US-20080153806-A1 | Novel Diazabicyclic Aryl Derivatives And Their Medical Use | NEUROSEARCH A/S (DK) | 2008-06-26 | — | — | US | claimed |
| EP-1805183-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES AND THEIR MEDICAL USE | NeuroSearch A/S (DK) | 2007-07-11 | — | — | EP | claimed |
| WO-2006045716-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2006-05-04 | — | — | WO | claimed |
| EP-1805183-B1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH AS (DK) | 2010-12-29 | — | — | EP | disclosed |
| US-20080153806-A1 | Novel Diazabicyclic Aryl Derivatives And Their Medical Use | NEUROSEARCH A/S (DK) | 2008-06-26 | — | — | US | disclosed |
| EP-1805183-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES AND THEIR MEDICAL USE | NeuroSearch A/S (DK) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006045716-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153806-A1 | Novel Diazabicyclic Aryl Derivatives And Their Medical Use | CHRNA6, CHRNA10, CHRNA2 | SCD 1122/4885CHRNA7 6/4885HTR3A 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.