Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 17/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394176 | 1.00 | CCR5 (0.49) | CCR5KDM4EOPRL1 | |
| Hydrochloric Acid SCHEMBL3393730 | 0.99 | CCR5 (0.49) | CCR5KDM4EOPRL1 | |
| Hydrochloric Acid SCHEMBL3393732 | 0.99 | CCR5 (0.49) | CCR5KDM4EOPRL1 | |
| SCHEMBL3390270 | 0.90 | CCR5 (0.44) | CCR5OPRL1 | |
| SCHEMBL3394536 | 0.89 | CCR5 (0.44) | CCR5OPRL1 | |
| SCHEMBL3394539 | 0.89 | CCR5 (0.44) | CCR5OPRL1 | |
| Hydrochloric Acid SCHEMBL3393387 | 0.89 | CCR5 (0.44) | CCR5OPRL1 | |
| Hydrochloric Acid SCHEMBL3393876 | 0.88 | CCR5 (0.44) | CCR5OPRL1 | |
| Hydrochloric Acid SCHEMBL3393874 | 0.88 | CCR5 (0.44) | CCR5OPRL1 | |
| SCHEMBL3391654 | 0.88 | CCR5 (0.49) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709642-B2 | Spirohydantoin compounds and methods for the modulation of chemokine receptor activity | VIROCHEM PHARMA, INC. (CA) | 2010-05-04 | — | — | US | claimed |