SCHEMBL33943

SCHEMBL33943

Cc1cc(N)c(C)cc1N

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.86
TSHR P16473 4/20 0.86
MAPK1 P28482 1/20 0.86
ALDH1A1 P00352 8/20 0.63
ALOX15 P16050 2/20 0.55
CYP1A2 P05177 1/20 0.55
CASP7 P55210 1/20 0.55
HIF1A Q16665 1/20 0.55
HSD17B10 Q99714 1/20 0.55
TDP1 Q9NUW8 5/20 0.53
CASP1 P29466 1/20 0.53
CD44 P16070 1/20 0.53
TERT O14746 1/20 0.52
UHRF1 Q96T88 1/20 0.48
ATAD2 Q6PL18 1/20 0.46
TP53 P04637 2/20 0.44
PTK2 Q05397 1/20 0.43
MAPT P10636 2/20 0.42
GAA P10253 2/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8640327 0.96 CYP3A4 (0.80) CYP3A4TSHRMAPK1ALDH1A1ALOX15
Hydrochloric Acid SCHEMBL8640325 0.96 CYP3A4 (0.80) CYP3A4TSHRMAPK1ALDH1A1ALOX15
SCHEMBL2386087 0.93 CYP3A4 (0.75) CYP3A4TSHRMAPK1ALDH1A1ALOX15
SCHEMBL113803 0.93 CYP3A4 (1.00) CYP3A4TSHRMAPK1ALDH1A1ALOX15
SCHEMBL29452873 0.93 CYP3A4 (0.75) CYP3A4TSHRMAPK1ALDH1A1ALOX15
SCHEMBL439013 0.88 CYP3A4 (0.80) CYP3A4TSHRMAPK1ALDH1A1ALOX15
SCHEMBL16464361 0.87 CYP3A4 (0.67) CYP3A4TSHRMAPK1ALDH1A1ALOX15
SCHEMBL3101719 0.87 CYP3A4 (0.67) CYP3A4TSHRMAPK1ALDH1A1ALOX15
Hydrochloric Acid SCHEMBL31703327 0.85 CYP3A4 (0.75) CYP3A4TSHRMAPK1ALDH1A1ALOX15
SCHEMBL272760 0.84 CYP3A4 (0.63) CYP3A4TSHRMAPK1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8288 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122076269-A Covalent organic framework mixed matrix membrane, in-situ growth method thereof and application thereof in ion separation 2026-05-26 CN claimed
CN-117398864-B Thermal crosslinking semi-interpenetrating helium separation membrane and preparation method and application thereof 江南大学 2026-05-15 CN claimed
CN-122011311-A Preparation method of metal nanocluster confined covalent organic framework composite material 西北工业大学 2026-05-12 CN claimed
US-12624144-B2 Method for preparing hollow covalent organic framework materials ZHEJIANG UNIVERSITY (CN) 2026-05-12 US claimed
CN-120157818-A Preparation of covalent organic framework material containing methyl and thiophene and application of covalent organic framework material in production of hydrogen peroxide 哈尔滨理工大学 2025-06-17 CN claimed
CN-120054245-A COF bionic membrane with artificial water channel and preparation method and application thereof 海南大学 2025-05-30 CN claimed
CN-120040699-A Covalent organic framework material and preparation method and application thereof 贵州师范学院 2025-05-27 CN claimed
CN-119857381-A Gas separation membrane based on covalent organic framework and preparation method and application thereof 天津大学 2025-04-22 CN claimed
CN-119842073-A Polyimide film and preparation method and application thereof 中南大学 2025-04-18 CN claimed
WO-2025058250-A1 HEAT-SEALABLE POLYIMIDE ADHESIVE FILM AND METHOD FOR MANUFACTURING SAME (주)아이피아이테크 2025-03-20 WO claimed
US-4865617-A Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers L'OREAL (FR) 1989-09-12 US claimed
US-4865619-A Use, as a coupler, of 2,4-diamino-1,3-dimethoxybenzene or one of its salts, in combination with oxidation dye precursors, for dyeing human hair, hair dyeing composition containing the said coupler and process for preparing the said coupler L'OREAL (FR) 1989-09-12 US claimed
EP-0295474-A1 Chlorometaphenylenediamines, their use as coupling agents in oxydation colouring of keratinic fibres, colourity compositions for hair containing these compounds and colouring process using these compositions L'OREAL (FR) 1988-12-21 EP claimed
EP-0294669-A1 Metaphenylendiamines, process for their preparation, intermediate compounds and use of these metaphenylendiamines as couplers in oxydative colouring of keratinic fibres especially of human hair L'OREAL (FR) 1988-12-14 EP claimed
US-4692166-A OXIDATION COLOR DYES USED WITH DIAMINOBENZENES OR AMINO PHENOLS; MINIMIZATION OF RED HUE L'OREAL (FR) 1987-09-08 US claimed
EP-0040173-B1 DISAZO PIGMENT, METHOD FOR ITS PREPARATION AND ITS USE CIBA-GEIGY AG (CH) 1983-07-27 EP claimed
EP-0040173-A1 Disazo pigment, method for its preparation and its use CIBA-GEIGY AG (CH) 1981-11-18 EP claimed
US-4200432-A HAIR DYES L'OREAL (FR) 1980-04-29 US claimed
US-3961879-A P-PHENYLENEDIAMINE, HAIR L'OREAL (FR) 1976-06-08 US claimed
US-3948596-A Oxidation dye for keratinic fibers containing 2-halo-5-acetaminophenol as a coupler SOCIETE ANONYME DITE: L'OREAL (FR) 1976-04-06 US claimed