⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391444 | 0.82 | TDP1 (0.34) | — | |
| SCHEMBL4953043 | 0.77 | MAPT (0.42) | — | |
| SCHEMBL4951683 | 0.76 | ADH1B (0.32) | — | |
| SCHEMBL4949463 | 0.76 | CYP2C9 (0.42) | — | |
| SCHEMBL18901740 | 0.74 | RNPEP (0.34) | — | |
| SCHEMBL4952926 | 0.74 | OR51E2 (0.30) | — | |
| SCHEMBL3391868 | 0.74 | — | — | |
| SCHEMBL4955458 | 0.73 | HDAC3 (0.40) | — | |
| SCHEMBL4954094 | 0.73 | ACE (0.33) | — | |
| SCHEMBL4954486 | 0.73 | TP53 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560558-B1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2010-12-29 | — | — | EP | claimed |
| EP-1560558-A4 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2008-09-24 | — | — | EP | claimed |
| JP-2006508103-A | — | — | 2006-03-09 | — | — | JP | claimed |
| US-6987090-B2 | Use of 3-position cyclosporin derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2006-01-17 | — | — | US | claimed |
| EP-1560558-A1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG Household & Health Care Ltd. (KR) | 2005-08-10 | — | — | EP | claimed |
| WO-2004041221-A1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2004-05-21 | — | — | WO | claimed |
| US-20040087496-A1 | Use of 3-position cyclosporin derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2004-05-06 | — | — | US | claimed |
| EP-1560558-B1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2010-12-29 | — | — | EP | disclosed |
| EP-1560558-A4 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2008-09-24 | — | — | EP | disclosed |
| US-6987090-B2 | Use of 3-position cyclosporin derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2006-01-17 | — | — | US | disclosed |
| EP-1560558-A1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG Household & Health Care Ltd. (KR) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004041221-A1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2004-05-21 | — | — | WO | disclosed |
| US-20040087496-A1 | Use of 3-position cyclosporin derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2004-05-06 | — | — | US | disclosed |