Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | USP9X | Q93008 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3204590 | 0.92 | HTR6 (0.43) | HTR6PPARGPPARDPPARACHRM5 | |
| SCHEMBL3216028 | 0.91 | HTR6 (0.42) | HTR6AKT1PIK3CAMTORNAMPT | |
| SCHEMBL3394942 | 0.85 | HTR6 (0.33) | HTR6PPARGPPARDPPARACHRM5 | |
| SCHEMBL3208578 | 0.84 | PPARG (0.46) | HTR6PPARGPPARDPPARACHRM5 | |
| SCHEMBL3212422 | 0.81 | HTR6 (0.46) | HTR6PPARGPPARDPPARA | |
| SCHEMBL3193049 | 0.81 | HTR6 (0.44) | HTR6PPARGPPARDPPARACHRM5 | |
| SCHEMBL3203444 | 0.80 | HTR6 (0.42) | HTR6 | |
| SCHEMBL3205282 | 0.80 | HTR6 (0.41) | HTR6PPARGPPARDPPARACHRM5 | |
| SCHEMBL3200614 | 0.80 | HTR6 (0.41) | HTR6AKT1PIK3CAMTORNAMPT | |
| SCHEMBL3214156 | 0.80 | HTR6 (0.41) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011546-A2 | ACYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-28 | — | — | WO | claimed |