Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 8/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28586185 | 0.77 | NPC1 (0.78) | MAOBMAOANPC1RAB9ATDP1 | |
| SCHEMBL2280993 | 0.76 | MRGPRX4 (0.52) | MAOBMAOARELANPC1RAB9A | |
| SCHEMBL7534312 | 0.76 | NQO2 (0.58) | NQO2RELATUBB4ATUBBTUBA3C | |
| SCHEMBL3394056 | 0.75 | TUBB1 (0.59) | NQO2LCKTUBB1NFE2L2CYP1A1 | |
| SCHEMBL18648519 | 0.75 | TUBB1 (0.59) | NQO2LCKTUBB1NFE2L2CYP1A1 | |
| SCHEMBL14989228 | 0.75 | NQO2 (1.00) | NQO2RELATUBB4ATUBBTUBA3C | |
| SCHEMBL8264358 | 0.75 | NQO2 (0.74) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13144444 | 0.73 | MAOB (0.87) | MAOBMAOA | |
| SCHEMBL14363441 | 0.73 | CYP1A1 (0.73) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16710547 | 0.73 | MAOB (0.71) | MAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245019-A1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009103626-A1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-08-27 | — | — | WO | disclosed |