SCHEMBL3395142

SCHEMBL3395142

CC(C)(Br)C(=O)OC1CC2C=CC1C2

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
EPHX2 P34913 2/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28742067 0.88 KDM4E (0.37) KDM4ELMNAEPHX2ALDH1A1
SCHEMBL14707437 0.85 KDM4E (0.35) KDM4ELMNAEPHX2
SCHEMBL7715396 0.85 KDM4E (0.35) KDM4ELMNAEPHX2
SCHEMBL7207896 0.82 KDM4E (0.33) KDM4ELMNA
SCHEMBL7213498 0.82 KDM4E (0.33) KDM4ELMNA
SCHEMBL7715397 0.81 KDM4E (0.33) KDM4ELMNA
SCHEMBL7716165 0.80 KDM4E (0.32) KDM4ELMNAEPHX2
SCHEMBL6550591 0.79 CHRM3 (0.34) KDM4ELMNA
SCHEMBL13791007 0.78 KDM4E (0.40) KDM4ELMNAEPHX2ALDH1A1TDP1
SCHEMBL301572 0.78 KDM4E (0.40) KDM4ELMNAEPHX2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2152763-B1 CONTROLLED FREE RADICAL GRAFTING FROM POLYOLEFINS UNIV CALIFORNIA (US) 2016-05-04 EP claimed
US-7825200-B2 olefins functionalized with free radical initiators, copolymerization with ethylene and subsequent grafting with butyl acrylate; initiating monomer is from 5-norbornen-2-ol; 5-norbornen-2-yl 4-(1-(1-(2,2,6,6-tetramethylpiperidinoxy))ethyl)benzyl ether; nickel complex catalyst THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-11-02 US claimed
EP-2152763-A2 CONTROLLED FREE RADICAL GRAFTING FROM POLYOLEFINS The Regents of the University of California (US) 2010-02-17 EP claimed
WO-2008088494-A2 CONTROLLED FREE RADICAL GRAFTING FROM POLYOLEFINS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-07-24 WO claimed
US-20070149732-A1 Controlled free radical grafting from polyolefins REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2007-06-28 US claimed
US-20230194985-A1 BRUSH POLYMER, PHOTORESIST COMPOSITION INCLUDING THE SAME, AND METHOD OF MANUFACTURING INTEGRATED CIRCUIT DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-06-22 US disclosed
US-20230194985-A1 BRUSH POLYMER, PHOTORESIST COMPOSITION INCLUDING THE SAME, AND METHOD OF MANUFACTURING INTEGRATED CIRCUIT DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-06-22 US disclosed
US-20230194985-A1 BRUSH POLYMER, PHOTORESIST COMPOSITION INCLUDING THE SAME, AND METHOD OF MANUFACTURING INTEGRATED CIRCUIT DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-06-22 US disclosed
EP-2152763-B1 CONTROLLED FREE RADICAL GRAFTING FROM POLYOLEFINS UNIV CALIFORNIA (US) 2016-05-04 EP disclosed
EP-2152763-B1 CONTROLLED FREE RADICAL GRAFTING FROM POLYOLEFINS UNIV CALIFORNIA (US) 2016-05-04 EP disclosed
US-7825200-B2 olefins functionalized with free radical initiators, copolymerization with ethylene and subsequent grafting with butyl acrylate; initiating monomer is from 5-norbornen-2-ol; 5-norbornen-2-yl 4-(1-(1-(2,2,6,6-tetramethylpiperidinoxy))ethyl)benzyl ether; nickel complex catalyst THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-11-02 US disclosed
US-7825200-B2 olefins functionalized with free radical initiators, copolymerization with ethylene and subsequent grafting with butyl acrylate; initiating monomer is from 5-norbornen-2-ol; 5-norbornen-2-yl 4-(1-(1-(2,2,6,6-tetramethylpiperidinoxy))ethyl)benzyl ether; nickel complex catalyst THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-11-02 US disclosed
EP-2152763-A2 CONTROLLED FREE RADICAL GRAFTING FROM POLYOLEFINS The Regents of the University of California (US) 2010-02-17 EP disclosed
WO-2008088494-A2 CONTROLLED FREE RADICAL GRAFTING FROM POLYOLEFINS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-07-24 WO disclosed
US-20070149732-A1 Controlled free radical grafting from polyolefins REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2007-06-28 US disclosed
US-20070149732-A1 Controlled free radical grafting from polyolefins REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2007-06-28 US disclosed