SCHEMBL7715396

SCHEMBL7715396

CC(C)(C)C(C)(C(=O)OC1CC2C=CC1C2)C(=O)OC1CC2C=CC1C2

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7715397 0.92 KDM4E (0.33) KDM4ELMNA
SCHEMBL28742067 0.86 KDM4E (0.37) KDM4ELMNAEPHX2
SCHEMBL3395142 0.85 KDM4E (0.36) KDM4ELMNAEPHX2
SCHEMBL14707437 0.83 KDM4E (0.35) KDM4ELMNAEPHX2
SCHEMBL7716165 0.81 KDM4E (0.32) KDM4ELMNAEPHX2
SCHEMBL7213498 0.81 KDM4E (0.33) KDM4ELMNA
SCHEMBL7207896 0.81 KDM4E (0.33) KDM4ELMNA
SCHEMBL7715385 0.80 POLB (0.30)
SCHEMBL7716170 0.79 KDM4E (0.30) KDM4ELMNA
SCHEMBL6550591 0.77 CHRM3 (0.34) KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376632-B1 NORBORNENE COMPOUND CONTAINING CARBOXY GROUPS HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-04-23 US disclosed