Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777377 | 0.86 | S1PR5 (0.41) | GRIN2BS1PR5S1PR1FUCA1KMT2A | |
| SCHEMBL16053284 | 0.82 | KCNK3 (0.55) | GRIN2BS1PR5S1PR1KCNK3KCNK9 | |
| SCHEMBL584450 | 0.82 | KCNK3 (0.55) | GRIN2BS1PR5S1PR1KCNK3KCNK9 | |
| SCHEMBL18517590 | 0.82 | GRIN2B (0.55) | GRIN2BS1PR5S1PR1FUCA1KMT2A | |
| SCHEMBL649847 | 0.82 | KCNK3 (0.55) | GRIN2BS1PR5S1PR1KCNK3KCNK9 | |
| Hydrochloric Acid SCHEMBL6093599 | 0.81 | KCNK3 (0.54) | GRIN2BS1PR5S1PR1KCNK3KCNK9 | |
| Hydrochloric Acid SCHEMBL6095348 | 0.81 | KCNK3 (0.54) | GRIN2BS1PR5S1PR1KCNK3KCNK9 | |
| SCHEMBL4717872 | 0.77 | SMN1; SMN2 (0.51) | KMT2A | |
| SCHEMBL17228284 | 0.77 | JAK2 (0.54) | KMT2AKCNK3KCNK9 | |
| SCHEMBL25173575 | 0.77 | S1PR5 (0.56) | S1PR5S1PR1FUCA1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758853-B1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | LILLY CO ELI (US) | 2010-01-20 | — | — | EP | disclosed |