Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27638264 | 0.90 | SMN1; SMN2 (0.54) | SMN1; SMN2RECQLACHEKDM4EALDH1A1 | |
| SCHEMBL3779080 | 0.84 | CHRM4 (0.56) | SMN1; SMN2RECQLACHEKDM4EALDH1A1 | |
| SCHEMBL7338535 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2RECQLACHEKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3966170 | 0.83 | CHRM4 (0.55) | SMN1; SMN2RECQLACHEKDM4EALDH1A1 | |
| SCHEMBL31333511 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2RECQLACHEKDM4EALDH1A1 | |
| SCHEMBL3570582 | 0.81 | ACHE (0.61) | SMN1; SMN2RECQLACHEKDM4EALDH1A1 | |
| SCHEMBL31334166 | 0.80 | CHRM4 (0.49) | SMN1; SMN2RECQLACHEKDM4EALDH1A1 | |
| SCHEMBL642728 | 0.80 | JAK2 (0.54) | SMN1; SMN2RECQLACHEKDM4EALDH1A1 | |
| SCHEMBL642727 | 0.80 | JAK2 (0.54) | SMN1; SMN2RECQLACHEKDM4EALDH1A1 | |
| SCHEMBL23689558 | 0.79 | KMT2A (0.61) | ACHEKDM4EALDH1A1CHRM4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943222-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2008-07-16 | — | — | EP | disclosed |
| EP-1558600-B1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007042325-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2007-04-19 | — | — | WO | disclosed |