Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13426197 | 0.91 | KIF11 (0.56) | KIF11ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL3394359 | 0.91 | KIF11 (0.56) | KIF11ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL13426932 | 0.91 | KIF11 (0.56) | KIF11ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL13425577 | 0.90 | KIF11 (0.53) | KIF11ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL13425605 | 0.88 | KIF11 (0.53) | KIF11ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL13426235 | 0.87 | KIF11 (0.56) | KIF11ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL13425600 | 0.80 | KIF11 (0.56) | KIF11ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL6348279 | 0.78 | HTT (0.57) | KIF11ALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL13425599 | 0.77 | TP53 (0.50) | ALDH1A1NPSR1TP53 | |
| SCHEMBL13425504 | 0.77 | KIF11 (0.55) | KIF11ALDH1A1ALOX15MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |