Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.65 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.65 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.65 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3433015 | 0.89 | EGFR (0.62) | EGFRERBB2 | |
| SCHEMBL3391872 | 0.89 | EGFR (0.73) | EGFRMAPK14ERBB2 | |
| SCHEMBL3392653 | 0.89 | EGFR (0.73) | EGFRMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL3390805 | 0.87 | EGFR (0.76) | EGFRERBB2 | |
| SCHEMBL3389265 | 0.87 | EGFR (0.60) | EGFRMAPK14ERBB2 | |
| SCHEMBL3431548 | 0.87 | EGFR (0.66) | EGFRERBB2 | |
| SCHEMBL3391878 | 0.85 | EGFR (0.63) | EGFRERBB2 | |
| SCHEMBL3395368 | 0.85 | EGFR (0.81) | EGFRERBB2 | |
| SCHEMBL3432393 | 0.84 | EGFR (0.66) | EGFRERBB2 | |
| SCHEMBL3392498 | 0.83 | EGFR (0.64) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167492-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | Hanmi Pharm. Co., Ltd. (KR) | 2010-03-31 | — | — | EP | claimed |
| WO-2008150118-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | HANMI PHARM. CO., LTD. (KR) | 2008-12-11 | — | — | WO | claimed |
| EP-2167492-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | Hanmi Pharm. Co., Ltd. (KR) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008150118-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | HANMI PHARM. CO., LTD. (KR) | 2008-12-11 | — | — | WO | disclosed |