SCHEMBL3395491

SCHEMBL3395491

CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@@H](Oc2cncc(-c3ccc(C)cn3)c2)SC[C@H]1OC(C)=O

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.34
CYP2A6 P11509 1/20 0.34
FYN P06241 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL315175 1.00 CYP3A4 (0.34) CYP3A4CYP2A6FYNCA1CA2
SCHEMBL3399106 0.90 DYRK1A (0.31)
SCHEMBL315022 0.90 DYRK1A (0.31)
SCHEMBL314889 0.89 CHRNA7 (0.33)
SCHEMBL3399341 0.89 CHRNA7 (0.33)
SCHEMBL2412465 0.89 DHODH (0.36) CYP3A4CYP2A6FYN
SCHEMBL2412464 0.89 DHODH (0.36) CYP3A4CYP2A6FYN
SCHEMBL2141249 0.88 XDH (0.38) CYP3A4
SCHEMBL2141252 0.88 XDH (0.38) CYP3A4
SCHEMBL3393927 0.88 FYN (0.36) CYP3A4FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2066683-B1 DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT FOURNIER LAB SA (FR) 2010-11-03 EP disclosed