Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393812 | 1.00 | TSHR (0.62) | TSHRALDH1A1MAPK1L3MBTL1CRHBP | |
| SCHEMBL3497340 | 0.90 | KLK7 (0.60) | TSHRKLK7CNR2 | |
| SCHEMBL28850896 | 0.86 | TSHR (0.61) | TSHRALDH1A1MAPK1L3MBTL1CRHBP | |
| SCHEMBL28144709 | 0.86 | KLK7 (0.43) | TSHRALDH1A1CRHBPCRHR2KLK7 | |
| SCHEMBL8465667 | 0.84 | LMNA (0.45) | TSHRALDH1A1KLK7MEN1KMT2A | |
| SCHEMBL4315175 | 0.84 | LMNA (0.44) | TSHRALDH1A1KLK7MEN1KMT2A | |
| SCHEMBL19520108 | 0.84 | LMNA (0.44) | TSHRALDH1A1KLK7MEN1KMT2A | |
| SCHEMBL28008662 | 0.84 | TSHR (0.50) | TSHRALDH1A1MAPK1L3MBTL1CRHBP | |
| SCHEMBL3276203 | 0.82 | TSHR (0.56) | TSHRALDH1A1MAPK1L3MBTL1CRHBP | |
| SCHEMBL5907612 | 0.82 | TSHR (0.44) | TSHRALDH1A1KLK7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054319-A2 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2010-05-14 | — | — | WO | claimed |