Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 8/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.73 |
| ▸ | LMNA | P02545 | 6/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | PGR | P06401 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | SHBG | P04278 | 2/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.56 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 3/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3395660 | 1.00 | HIF1A (1.00) | HIF1ACYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL13069730 | 1.00 | HIF1A (1.00) | HIF1ACYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL17714998 | 1.00 | HIF1A (1.00) | HIF1ACYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL8637937 | 1.00 | HIF1A (1.00) | HIF1ACYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL3406165 | 0.92 | HIF1A (0.85) | HIF1ACYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL137529 | 0.89 | KMT2A (0.84) | HIF1ACYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL17714999 | 0.89 | KMT2A (0.84) | HIF1ACYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL13150977 | 0.89 | KMT2A (0.84) | HIF1ACYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL137530 | 0.89 | KMT2A (0.84) | HIF1ACYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL10393880 | 0.89 | KMT2A (0.84) | HIF1ACYP3A4HSD17B10ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041055-A | SULFENYLATION, MICHAEL ADDITION, REACTION WITH THIOPHILE, HYDROLYSIS | THE UPJOHN COMPANY (US) | 1977-08-09 | — | — | US | claimed |
| CN-116410939-A | 3-sterone-delta 1 Dehydrogenase mutant and application thereof in synthesis of steroid C1,2 dehydrogenation drug intermediates | 中国科学院天津工业生物技术研究所 | 2023-07-11 | — | — | CN | disclosed |
| EP-2246359-A1 | Process for obtaining fluorometholone and intermediates therefor | Crystal Pharma, S.L.U. (ES) | 2010-11-03 | — | — | EP | disclosed |