Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.71 |
| ▸ | RAF1 | P04049 | 1/20 | 0.71 |
| ▸ | LCK | P06239 | 1/20 | 0.71 |
| ▸ | RET | P07949 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | KIT | P10721 | 1/20 | 0.71 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.71 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.71 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 2/20 | 0.43 |
| ▸ | GOT1 | P17174 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633813 | 0.87 | KDR (0.75) | KDRRAF1LCKRETCYP3A4 | |
| SCHEMBL633872 | 0.86 | KDR (0.59) | KDRRAF1LCKRETCYP3A4 | |
| Osi-930 SCHEMBL633719 | 0.83 | KDR (1.00) | KDRRAF1LCKRETCYP3A4 | |
| Osi-930 SCHEMBL29352171 | 0.83 | KDR (1.00) | KDRRAF1LCKRETCYP3A4 | |
| SCHEMBL1819542 | 0.82 | KDR (0.67) | KDRRAF1LCKRETCYP3A4 | |
| SCHEMBL633692 | 0.79 | KDR (0.45) | KDRRAF1LCKRETCYP3A4 | |
| SCHEMBL635166 | 0.79 | KIT (0.55) | KDRRAF1LCKRETCYP3A4 | |
| SCHEMBL5266238 | 0.79 | KDR (0.76) | KDRRAF1LCKRETCYP3A4 | |
| SCHEMBL27615043 | 0.79 | KDR (0.44) | KDRRAF1LCKRETCYP3A4 | |
| SCHEMBL3360039 | 0.78 | KDR (0.70) | KDRRAF1LCKRETCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010088000-A2 | ANTIFIBROTIC COMPOUNDS AND USES THEREOF | ANGION BIOMEDICA CORP. (US) | 2010-08-05 | — | — | WO | claimed |
| WO-2010088000-A2 | ANTIFIBROTIC COMPOUNDS AND USES THEREOF | ANGION BIOMEDICA CORP. (US) | 2010-08-05 | — | — | WO | disclosed |