Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3395339 | 0.88 | BACE1 (0.34) | CTSDBACE1 | |
| SCHEMBL2283866 | 0.80 | BACE1 (0.49) | CTSDBACE1 | |
| SCHEMBL2283872 | 0.80 | BACE1 (0.49) | CTSDBACE1 | |
| SCHEMBL3395835 | 0.76 | BACE1 (0.44) | CTSDBACE1KMT2A | |
| SCHEMBL3395833 | 0.75 | BACE1 (0.44) | CTSDBACE1KMT2A | |
| SCHEMBL2284524 | 0.73 | BACE1 (0.43) | CTSDBACE1KMT2A | |
| SCHEMBL2279812 | 0.73 | BACE1 (0.43) | CTSDBACE1 | |
| SCHEMBL2287387 | 0.72 | BACE1 (0.44) | CTSDBACE1 | |
| SCHEMBL3395908 | 0.72 | CTSD (0.32) | CTSDBACE1KMT2A | |
| SCHEMBL2288080 | 0.71 | BACE1 (0.36) | CTSDBACE1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245019-A1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009103626-A1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-08-27 | — | — | WO | disclosed |