SCHEMBL3395995

SCHEMBL3395995

COc1cc(C=Cc2cccc(C)c2)cc(OC)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 2/20 0.74
ABL1 P00519 2/20 0.69
BCR P11274 2/20 0.69
CYP1A1 P04798 3/20 0.63
CYP1B1 Q16678 3/20 0.63
NQO2 P16083 4/20 0.59
ALOX5 P09917 3/20 0.58
ESR1 P03372 2/20 0.58
TTR P02766 2/20 0.58
PTGS2 P35354 2/20 0.58
TUBB4A P04350 2/20 0.58
TUBB P07437 2/20 0.58
TUBA3C P0DPH7 2/20 0.58
TUBA1B P68363 2/20 0.58
TUBA4A P68366 2/20 0.58
TUBB4B P68371 2/20 0.58
TUBB3 Q13509 2/20 0.58
TUBB2A Q13885 2/20 0.58
TUBB8 Q3ZCM7 2/20 0.58
TUBA3E Q6PEY2 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12729822 0.90 KDM4E (0.71) RELAABL1BCRCYP1A1CYP1B1
SCHEMBL5465793 0.86 ABL1 (0.76) RELAABL1BCRCYP1A1CYP1B1
SCHEMBL5465788 0.86 ABL1 (0.76) RELAABL1BCRCYP1A1CYP1B1
SCHEMBL5499297 0.85 RELA (1.00) RELAABL1BCRCYP1A1CYP1B1
SCHEMBL5499301 0.85 RELA (1.00) RELAABL1BCRCYP1A1CYP1B1
SCHEMBL16362233 0.82 CYP1A1 (0.77) ABL1BCRCYP1A1CYP1B1NQO2
SCHEMBL21847980 0.82 PTGS1 (0.69) RELAALOX5PTGS2CYP1A2PTGS1
SCHEMBL1795130 0.82 PTGS1 (0.69) RELAALOX5PTGS2CYP1A2PTGS1
SCHEMBL1795132 0.82 PTGS1 (0.69) RELAALOX5PTGS2CYP1A2PTGS1
SCHEMBL23754270 0.81 ABL1 (1.00) ABL1BCRCYP1A1CYP1B1NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010046926-A2 NOVEL STILBENE ANALOGS APTUIT LAURUS PVT LTD (IN) 2010-04-29 WO disclosed