⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269781 | 0.78 | — | — | |
| SCHEMBL601133 | 0.62 | — | — | |
| SCHEMBL126646 | 0.61 | — | — | |
| SCHEMBL6631580 | 0.60 | — | — | |
| SCHEMBL4502875 | 0.56 | — | — | |
| SCHEMBL4984875 | 0.56 | — | — | |
| Benzene SCHEMBL5081287 | 0.42 | CA1 (0.71) | — | |
| Benzene SCHEMBL10964916 | 0.42 | CA1 (0.71) | — | |
| Benzene SCHEMBL10961254 | 0.42 | CA1 (0.71) | — | |
| Benzene SCHEMBL1122633 | 0.42 | CA1 (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206704-A1 | Pharmaceutically active diazepanes | Novartis AG (CH) | 2010-07-14 | — | — | EP | claimed |
| US-20080300237-A1 | Pharmaceutically Active Diazepanes | OBERHAUSER BERNDT | 2008-12-04 | — | — | US | claimed |
| EP-1874739-A1 | PHARMACEUTICALLY ACTIVE DIAZEPANES | Novartis AG (CH) | 2008-01-09 | — | — | EP | claimed |
| WO-2006111371-A1 | PHARMACEUTICALLY ACTIVE DIAZEPANES | NOVARTIS AG (CH) | 2006-10-26 | — | — | WO | claimed |
| JP-8176144-A | — | — | None | — | — | JP | disclosed |
| EP-2206704-A1 | Pharmaceutically active diazepanes | Novartis AG (CH) | 2010-07-14 | — | — | EP | disclosed |
| US-20080300237-A1 | Pharmaceutically Active Diazepanes | OBERHAUSER BERNDT | 2008-12-04 | — | — | US | disclosed |
| EP-1874739-A1 | PHARMACEUTICALLY ACTIVE DIAZEPANES | Novartis AG (CH) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006111371-A1 | PHARMACEUTICALLY ACTIVE DIAZEPANES | NOVARTIS AG (CH) | 2006-10-26 | — | — | WO | disclosed |
| EP-0710661-B1 | Amino acid derivative having anti-CKK activity | TOBISHI PHARMACEUTICAL CO (JP) | 1999-03-31 | — | — | EP | disclosed |
| US-5716958-A | GASTROINTESTINAL DISORDERS; INHIBITORY ACTIVITY ON CHOLECYSTOKININ | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| JP-H08176144-A | SERINE, ASPARTIC ACID AND GLUTAMIC ACID DERIVATIVE HAVING ANTI-CCK ACTIVITY | TOUBISHI YAKUHIN KOGYO KK | 1996-07-09 | — | — | JP | disclosed |
| EP-0710661-A1 | Amino acid derivative having anti-CKK activity | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-3869440-A | METAL-COMPLEX AZO DYESTUFFS CONTAINING A 5-SUBSTITUTED-2,3-DIHYDROXYPYRIDINE AS COUPLING COMPONENT | CIBA GEIGY AG | 1975-03-04 | — | — | US | disclosed |