Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132009 | 0.77 | SLC22A6 (0.39) | — | |
| SCHEMBL3902488 | 0.75 | ALOX15 (0.41) | — | |
| SCHEMBL10034531 | 0.74 | ECE1 (0.35) | ECE1 | |
| SCHEMBL19554508 | 0.72 | ECE1 (0.37) | ECE1 | |
| SCHEMBL2467277 | 0.72 | TSHR (0.43) | ECE1 | |
| SCHEMBL12234129 | 0.72 | ECE1 (0.33) | ECE1 | |
| SCHEMBL13007435 | 0.72 | ECE1 (0.33) | ECE1 | |
| SCHEMBL15774508 | 0.72 | ECE1 (0.33) | ECE1 | |
| SCHEMBL7518485 | 0.70 | — | — | |
| SCHEMBL7515032 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2244708-A1 | NEW 2,3,4,5-TEtRAHYDRO-1H-PYRIDO [4,3-B] INDOLE COMPOUNDS AND METHODS OF USE THEREOF | Medivation Technologies, Inc. (US) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009094668-A1 | NEW 2,3,4,5-TERAHYDRO-1H-PYRIDO[ 4,3-B] INDOLE COMPOUNDS AND METHODS OF USE THEREOF | MEDIVATION TECHNOLOGIES, INC. (US) | 2009-07-30 | — | — | WO | disclosed |