Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2527268 | 0.93 | CHRM2 (0.33) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4490426 | 0.84 | — | — | |
| SCHEMBL2525036 | 0.77 | CHRM2 (0.32) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL3394216 | 0.77 | MAPK1 (0.36) | — | |
| SCHEMBL844572 | 0.76 | KDM4E (0.30) | — | |
| SCHEMBL3397819 | 0.75 | SLC6A4 (0.33) | — | |
| SCHEMBL13070118 | 0.74 | TSHR (0.30) | — | |
| SCHEMBL3745117 | 0.73 | BACE1 (0.31) | — | |
| SCHEMBL3745120 | 0.70 | — | — | |
| SCHEMBL13070122 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410289-B2 | Spirocyclic 3'-alkoxytetramic acids and-tetronic acids | BAYER CROPSCIENCE AG (DE) | 2013-04-02 | — | — | US | disclosed |
| EP-2246328-A1 | 3'-Alkoxy spirocyclic tetronic acid derivatives | Bayer CropScience AG (DE) | 2010-11-03 | — | — | EP | disclosed |
| US-20090029858-A1 | Spirocyclic 3'-Alkoxytetramic Acids and -Tetronic Acids | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-01-29 | — | — | US | disclosed |
| EP-1761490-A1 | 3'-ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACIDS | Bayer CropScience Aktiengesellschaft (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006000355-A1 | 3'-ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029858-A1 | Spirocyclic 3'-Alkoxytetramic Acids and -Tetronic Acids | DDT, MTX1, MTX2 | CHRM2 100/4885CHRM4 667/4885CHRM5 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.